Literature DB >> 16060370

En masse analysis of nascent translation using microarrays.

Krystyna Mazan-Mamczarz1, Tomoko Kawai, Jennifer L Martindale, Myriam Gorospe.   

Abstract

We report a robust method for studying en masse changes in translation using cDNA arrays. The relative distribution of messenger RNAs (mRNAs) along polysome gradients was monitored by performing cDNA array analysis of each gradient fraction and quantifying the mRNA translational status by regression analysis. Using this strategy to study human carcinoma cells exposed to short-wavelength ultraviolet light (UVC), we identified a subset of 17 translationally induced mRNAs and a subset of 69 translationally repressed mRNAs following UVC irradiation. We describe an effective approach for globally investigating changes in protein biosynthesis.

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Year:  2005        PMID： 16060370      PMCID： PMC1350913          DOI： 10.2144/05391ST01

Source DB:  PubMed          Journal:  Biotechniques        ISSN： 0736-6205            Impact factor:   1.993


  8 in total

1.  Messenger RNA translation state: the second dimension of high-throughput expression screening.

Authors:  Q Zong; M Schummer; L Hood; D R Morris
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-14       Impact factor: 11.205

2.  Protein analysis by mass spectrometry and sequence database searching: tools for cancer research in the post-genomic era.

Authors:  S P Gygi; D K Han; A C Gingras; N Sonenberg; R Aebersold
Journal:  Electrophoresis       Date:  1999-02       Impact factor: 3.535

3.  Analysis of microarray data using Z score transformation.

Authors:  Chris Cheadle; Marquis P Vawter; William J Freed; Kevin G Becker
Journal:  J Mol Diagn       Date:  2003-05       Impact factor: 5.568

4.  Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae.

Authors:  Yoav Arava; Yulei Wang; John D Storey; Chih Long Liu; Patrick O Brown; Daniel Herschlag
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-26       Impact factor: 11.205

5.  Global mRNA stabilization preferentially linked to translational repression during the endoplasmic reticulum stress response.

Authors:  Tomoko Kawai; Jinshui Fan; Krystyna Mazan-Mamczarz; Myriam Gorospe
Journal:  Mol Cell Biol       Date:  2004-08       Impact factor: 4.272

Review 6.  Regulation of translation initiation factors by signal transduction.

Authors:  M Kleijn; G C Scheper; H O Voorma; A A Thomas
Journal:  Eur J Biochem       Date:  1998-05-01

7.  Influence of the RNA-binding protein HuR in pVHL-regulated p53 expression in renal carcinoma cells.

Authors:  Stefanie Galbán; Jennifer L Martindale; Krystyna Mazan-Mamczarz; Isabel López de Silanes; Jinshui Fan; Wengong Wang; Jochen Decker; Myriam Gorospe
Journal:  Mol Cell Biol       Date:  2003-10       Impact factor: 4.272

8.  RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation.

Authors:  Krystyna Mazan-Mamczarz; Stefanie Galbán; Isabel López de Silanes; Jennifer L Martindale; Ulus Atasoy; Jack D Keene; Myriam Gorospe
Journal:  Proc Natl Acad Sci U S A       Date:  2003-06-23       Impact factor: 12.779
  8 in total
  6 in total

1.  Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR.

Authors:  Tomoko Kawai; Ashish Lal; Xiaoling Yang; Stefanie Galban; Krystyna Mazan-Mamczarz; Myriam Gorospe
Journal:  Mol Cell Biol       Date:  2006-04       Impact factor: 4.272

2.  Translational repression by RNA-binding protein TIAR.

Authors:  Krystyna Mazan-Mamczarz; Ashish Lal; Jennifer L Martindale; Tomoko Kawai; Myriam Gorospe
Journal:  Mol Cell Biol       Date:  2006-04       Impact factor: 4.272

3.  Cytoplasmic relocalization of heterogeneous nuclear ribonucleoprotein A1 controls translation initiation of specific mRNAs.

Authors:  Anne Cammas; Frédéric Pileur; Sophie Bonnal; Stephen M Lewis; Nicolas Lévêque; Martin Holcik; Stéphan Vagner
Journal:  Mol Biol Cell       Date:  2007-09-26       Impact factor: 4.138

4.  eIF2alpha kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver.

Authors:  An N Dang Do; Scot R Kimball; Douglas R Cavener; Leonard S Jefferson
Journal:  Physiol Genomics       Date:  2009-06-09       Impact factor: 3.107

5.  Translational regulation of the mRNA encoding the ubiquitin peptidase USP1 involved in the DNA damage response as a determinant of Cisplatin resistance.

Authors:  Tony Sourisseau; Carole Helissey; Céline Lefebvre; Florence Ponsonnailles; Hélène Malka-Mahieu; Ken A Olaussen; Fabrice André; Stephan Vagner; Jean-Charles Soria
Journal:  Cell Cycle       Date:  2016       Impact factor: 4.534

6.  Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line.

Authors:  Christine Vogel; Raquel de Sousa Abreu; Daijin Ko; Shu-Yun Le; Bruce A Shapiro; Suzanne C Burns; Devraj Sandhu; Daniel R Boutz; Edward M Marcotte; Luiz O Penalva
Journal:  Mol Syst Biol       Date:  2010-08-24       Impact factor: 11.429
  6 in total

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