Literature DB >> 1605284

The safety of oral contraceptives: epidemiologic insights from the first 30 years.

D A Grimes1.   

Abstract

Because oral contraceptives are used by tens of millions of healthy women, their safety for short-term and long-term use is an important issue that has been examined in a large number of epidemiologic studies. These studies have become more rigorous and have increased in size and analytic sophistication over the years. Although breast cancer remains the most important safety concern, the bulk of recent data suggests that oral contraceptives have no overall impact on a woman's risk of developing this disease. The results are less clear on the risk of cervical cancer and its precursors because of methodologic problems. However, the newer oral contraceptive formulations no longer appear to be associated with an increased risk of myocardial infarction or stroke.

Entities:  

Keywords:  Americas; Behavior; Biology; Breast Cancer; Cancer; Cardiovascular Effects; Cervical Cancer; Contraception; Contraceptive Methods--beneficial effects; Contraceptive Methods--side effects; Developed Countries; Developing Countries; Diseases; Dysmenorrhea; Epidemiologic Methods; Europe; Evaluation; Family Planning; Hemic System; Hemoglobin Level; Infections; Infertility; Literature Review; Liver Neoplasms; Menstruation Disorders; Neoplasms; Neoplasms, Benign; North America; Northern America; Northern Europe; Oral Contraceptives--beneficial effects; Oral Contraceptives--side effects; Ovarian Cancer; Ovarian Cysts; Pelvic Infections; Physiology; Pregnancy Complications; Pregnancy, Ectopic; Reproduction; Research Methodology; Risk Assessment; Smoking; United Kingdom; United States

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Year:  1992        PMID: 1605284     DOI: 10.1016/0002-9378(92)91394-p

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  6 in total

1.  Perceptions of hormonal contraceptive safety and side effects among low-income Latina and non-Latina women.

Authors:  S Guendelman; C Denny; J Mauldon; C Chetkovich
Journal:  Matern Child Health J       Date:  2000-12

Review 2.  The combined oral contraceptive. Risks and adverse effects in perspective.

Authors:  S Bagshaw
Journal:  Drug Saf       Date:  1995-02       Impact factor: 5.606

3.  Over-the-counter oral contraceptives--an immodest proposal?

Authors:  D A Grimes
Journal:  Am J Public Health       Date:  1993-08       Impact factor: 9.308

4.  Should oral contraceptives be available without prescription?

Authors:  J Trussell; F Stewart; M Potts; F Guest; C Ellertson
Journal:  Am J Public Health       Date:  1993-08       Impact factor: 9.308

5.  Implications of employer coverage of contraception: Cost-effectiveness analysis of contraception coverage under an employer mandate.

Authors:  W Canestaro; E Vodicka; D Downing; J Trussell
Journal:  Contraception       Date:  2016-08-16       Impact factor: 3.375

6.  Long term sequelae of sex steroid treatment in the management of constitutionally tall stature.

Authors:  W J de Waal; M Torn; S M de Muinck Keizer-Schrama; R S Aarsen; S L Drop
Journal:  Arch Dis Child       Date:  1995-10       Impact factor: 3.791

  6 in total

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