OBJECTIVE: This study was carried out to evaluate a procedure for converting bioimpedance spectroscopy (BIS) data to a clinically useful measure of fluid status that is easily interpreted by nursing staff and patients. DESIGN: The ratio of extracellular water (ECW) to total body water (TBW) in a cohort of peritoneal dialysis (PD) patients was compared with the distribution for normal control subjects. The result was expressed as the difference between the measured ECW/TBW ratio and the mean ratio for age- and sex-matched controls divided by the standard deviation for the controls (the "hydration score"). Where possible, interventions were made to reduce the target weight in patients with a hydration score greater than +2.0. SETTING: This clinical study was carried out in the nurse-led outpatient PD unit at St. James's University Hospital. BIS measurements were carried out during routine clinic visits. The data for the control subjects were obtained in a range of settings in the UK and the Czech Republic. PATIENTS: 31 PD patients (21 M, 10 F; aged 19 - 78 years) who came to the PD unit for routine procedures during the study participated. RESULTS: The mean hydration score for PD patients was significantly higher than for the control subjects (+1.3 vs 0.0, p < 0.0001). 11 (35%) patients had a hydration score greater than +2.0, compared with only 2.5% of the controls; systolic blood pressure was greater than 130 mmHg in only two of these patients. After a 3-month follow-up, a weight reduction of 3.6 +/- 2.3 kg had been achieved in 7 patients through modality change and implementation of prescription changes, with no adverse effects. CONCLUSIONS: Although this was a small study, all the data collected indicated that the hydration score provides a reliable indication of fluid status in PD patients. BIS measurements are now carried out at 6-month intervals and are used to monitor the effect of interventions.
OBJECTIVE: This study was carried out to evaluate a procedure for converting bioimpedance spectroscopy (BIS) data to a clinically useful measure of fluid status that is easily interpreted by nursing staff and patients. DESIGN: The ratio of extracellular water (ECW) to total body water (TBW) in a cohort of peritoneal dialysis (PD) patients was compared with the distribution for normal control subjects. The result was expressed as the difference between the measured ECW/TBW ratio and the mean ratio for age- and sex-matched controls divided by the standard deviation for the controls (the "hydration score"). Where possible, interventions were made to reduce the target weight in patients with a hydration score greater than +2.0. SETTING: This clinical study was carried out in the nurse-led outpatientPD unit at St. James's University Hospital. BIS measurements were carried out during routine clinic visits. The data for the control subjects were obtained in a range of settings in the UK and the Czech Republic. PATIENTS: 31 PDpatients (21 M, 10 F; aged 19 - 78 years) who came to the PD unit for routine procedures during the study participated. RESULTS: The mean hydration score for PDpatients was significantly higher than for the control subjects (+1.3 vs 0.0, p < 0.0001). 11 (35%) patients had a hydration score greater than +2.0, compared with only 2.5% of the controls; systolic blood pressure was greater than 130 mmHg in only two of these patients. After a 3-month follow-up, a weight reduction of 3.6 +/- 2.3 kg had been achieved in 7 patients through modality change and implementation of prescription changes, with no adverse effects. CONCLUSIONS: Although this was a small study, all the data collected indicated that the hydration score provides a reliable indication of fluid status in PDpatients. BIS measurements are now carried out at 6-month intervals and are used to monitor the effect of interventions.
Authors: Biju John; B Kay Tan; Stephen Dainty; Patrik Spanel; David Smith; Simon J Davies Journal: Clin J Am Soc Nephrol Date: 2010-06-10 Impact factor: 8.237
Authors: Isabel Cornejo-Pareja; Isabel M Vegas-Aguilar; Henry Lukaski; Antonio Talluri; Diego Bellido-Guerrero; Francisco J Tinahones; Jose Manuel García-Almeida Journal: Nutrients Date: 2022-06-30 Impact factor: 6.706
Authors: Ana Paula Bernardo; Jose C Oliveira; Olivia Santos; Maria J Carvalho; Antonio Cabrita; Anabela Rodrigues Journal: Clin J Am Soc Nephrol Date: 2015-10-27 Impact factor: 8.237
Authors: Man Ching Law; Bonnie Ching-Ha Kwan; Janny Suk-Fun Fung; Kai Ming Chow; Jack K C Ng; Wing-Fai Pang; Phyllis Mei-Shan Cheng; Chi Bon Leung; Cheuk Chun Szeto Journal: BMC Nephrol Date: 2019-12-09 Impact factor: 2.388