Literature DB >> 16045073

Rethinking the duration requirement for generalized anxiety disorder: evidence from the National Comorbidity Survey Replication.

Ronald C Kessler1, Nancy Brandenburg, Michael Lane, Peter Roy-Byrne, Paul D Stang, Dan J Stein, Hans-Ulrich Wittchen.   

Abstract

BACKGROUND: The proposed revisions of the ICD and DSM diagnostic systems have led to increased interest in evaluation of diagnostic criteria. This report focuses on the DSM-IV requirement that episodes of generalized anxiety disorder (GAD) must persist for at least 6 months. Community epidemiological data are used to study the implications of changing this requirement in the range 1-12 months for estimates of prevalence, onset, course, impairment, co-morbidity, associations with parental GAD, and sociodemographic correlates.
METHOD: Data come from the US National Comorbidity Survey Replication (NCS-R), a US household survey carried out during 2001-2003. Version 3.0 of the WHO Composite International Diagnostic Interview (WMH-CIDI) was used to assess DSM-IV anxiety disorders, mood disorders, substance disorders, and impulse-control disorders.
RESULTS: Lifetime, 12-month, and 30-day prevalence estimates of DSM-IV GAD changed from 6.1%, 2.9%, and 1.8% to 4.2-12.7%, 2.2-5.5%, and 1.6-2.6% when the duration requirement was changed from 6 months to 1-12 months. Cases with episodes of 1-5 months did not differ greatly from those with episodes of > or = 6 months in onset, persistence, impairment, co-morbidity, parental GAD, or sociodemographic correlates.
CONCLUSIONS: A large number of people suffer from a GAD-like syndrome with episodes of < 6 months duration. Little basis for excluding these people from a diagnosis is found in the associations examined here.

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Mesh:

Year:  2005        PMID: 16045073     DOI: 10.1017/s0033291705004538

Source DB:  PubMed          Journal:  Psychol Med        ISSN: 0033-2917            Impact factor:   7.723


  46 in total

1.  Broadening the definition of generalized anxiety disorder: effects on prevalence and associations with other disorders in the National Comorbidity Survey Replication.

Authors:  Ayelet Meron Ruscio; Wai Tat Chiu; Peter Roy-Byrne; Paul E Stang; Dan J Stein; Hans-Ulrich Wittchen; Ronald C Kessler
Journal:  J Anxiety Disord       Date:  2006-11-21

2.  Sympathetic activation in broadly defined generalized anxiety disorder.

Authors:  Walton T Roth; Sigrun Doberenz; Anja Dietel; Ansgar Conrad; Anett Mueller; Eileen Wollburg; Alicia E Meuret; C Barr Taylor; Sunyoung Kim
Journal:  J Psychiatr Res       Date:  2007-01-23       Impact factor: 4.791

3.  Prevalence, subtypes, and correlates of DSM-IV conduct disorder in the National Comorbidity Survey Replication.

Authors:  Matthew K Nock; Alan E Kazdin; Eva Hiripi; Ronald C Kessler
Journal:  Psychol Med       Date:  2006-01-26       Impact factor: 7.723

Review 4.  Anxiety and anxiety disorders in children and adolescents: developmental issues and implications for DSM-V.

Authors:  Katja Beesdo; Susanne Knappe; Daniel S Pine
Journal:  Psychiatr Clin North Am       Date:  2009-09

5.  Should excessive worry be required for a diagnosis of generalized anxiety disorder? Results from the US National Comorbidity Survey Replication.

Authors:  Ayelet Meron Ruscio; Michael Lane; Peter Roy-Byrne; Paul E Stang; Dan J Stein; Hans-Ulrich Wittchen; Ronald C Kessler
Journal:  Psychol Med       Date:  2005-12       Impact factor: 7.723

6.  Neuropeptide S Induces Acute Anxiolysis by Phospholipase C-Dependent Signaling within the Medial Amygdala.

Authors:  Thomas Grund; Inga D Neumann
Journal:  Neuropsychopharmacology       Date:  2017-08-14       Impact factor: 7.853

7.  The impact of resilience and subsequent stressful life events on MDD and GAD.

Authors:  Christina M Sheerin; Mackenzie J Lind; Emily A Brown; Charles O Gardner; Kenneth S Kendler; Ananda B Amstadter
Journal:  Depress Anxiety       Date:  2017-11-24       Impact factor: 6.505

8.  An examination of the etiologic overlap between the genetic and environmental influences on insomnia and common psychopathology.

Authors:  Mackenzie J Lind; Sage E Hawn; Christina M Sheerin; Steven H Aggen; Robert M Kirkpatrick; Kenneth S Kendler; Ananda B Amstadter
Journal:  Depress Anxiety       Date:  2017-01-16       Impact factor: 6.505

9.  Neuropeptide S-mediated control of fear expression and extinction: role of intercalated GABAergic neurons in the amygdala.

Authors:  Kay Jüngling; Thomas Seidenbecher; Ludmila Sosulina; Jörg Lesting; Susan Sangha; Stewart D Clark; Naoe Okamura; Dee M Duangdao; Yan-Ling Xu; Rainer K Reinscheid; Hans-Christian Pape
Journal:  Neuron       Date:  2008-07-31       Impact factor: 17.173

10.  Neuropeptide S Activates Paraventricular Oxytocin Neurons to Induce Anxiolysis.

Authors:  Thomas Grund; Stephanie Goyon; Yuting Li; Marina Eliava; Haikun Liu; Alexandre Charlet; Valery Grinevich; Inga D Neumann
Journal:  J Neurosci       Date:  2017-11-08       Impact factor: 6.167

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