BACKGROUND: To examine the association between anxiety (ANX) and bipolar disorders (BPD) in a clinically referred pediatric sample. METHODS: Subjects were consecutively referred youth aged <18 years, with a DSM-III-R/DSM-IV diagnosis of BPD (n=297) or a disruptive behavior disorder (DBD) (n=1100) on structured interview. RESULTS: Bipolar disorder in youth was associated with a significantly increased risk for most of the DSM-IV anxiety disorders and was not specifically linked to any one disorder in particular. CONCLUSIONS: Bipolar disorder in youth is a significant risk factor for anxiety comorbidity. Considering the morbidity and dysfunction as well as the differing therapeutic needs associated with bipolar and anxiety symptomatology, appropriate therapeutic approaches will be needed for the management of youth with this comorbidity.
BACKGROUND: To examine the association between anxiety (ANX) and bipolar disorders (BPD) in a clinically referred pediatric sample. METHODS: Subjects were consecutively referred youth aged <18 years, with a DSM-III-R/DSM-IV diagnosis of BPD (n=297) or a disruptive behavior disorder (DBD) (n=1100) on structured interview. RESULTS:Bipolar disorder in youth was associated with a significantly increased risk for most of the DSM-IV anxiety disorders and was not specifically linked to any one disorder in particular. CONCLUSIONS:Bipolar disorder in youth is a significant risk factor for anxiety comorbidity. Considering the morbidity and dysfunction as well as the differing therapeutic needs associated with bipolar and anxiety symptomatology, appropriate therapeutic approaches will be needed for the management of youth with this comorbidity.
Authors: Daniel P Dickstein; Elizabeth C Finger; Martha Skup; Daniel S Pine; James R Blair; Ellen Leibenluft Journal: Bipolar Disord Date: 2010-11 Impact factor: 6.744
Authors: Regina Sala; David A Axelson; Josefina Castro-Fornieles; Tina R Goldstein; Wonho Ha; Fangzi Liao; Mary Kay Gill; Satish Iyengar; Michael A Strober; Benjamin I Goldstein; Shirley Yen; Heather Hower; Jeffrey Hunt; Neal D Ryan; Daniel Dickstein; Martin B Keller; Boris Birmaher Journal: J Clin Psychiatry Date: 2010-09-07 Impact factor: 4.384
Authors: Daniel P Dickstein; Brendan A Rich; Roxann Roberson-Nay; Lisa Berghorst; Deborah Vinton; Daniel S Pine; Ellen Leibenluft Journal: Bipolar Disord Date: 2007-11 Impact factor: 6.744
Authors: Mona P Potter; Howard Y Liu; Michael C Monuteaux; Carly S Henderson; Janet Wozniak; Timothy E Wilens; Joseph Biederman Journal: J Child Adolesc Psychopharmacol Date: 2009-10 Impact factor: 2.576
Authors: Boris Birmaher; David Axelson; Michael Strober; Mary Kay Gill; Mei Yang; Neal Ryan; Benjamin Goldstein; Jeffrey Hunt; Christianne Esposito-Smythers; Satish Iyengar; Tina Goldstein; Laurel Chiapetta; Martin Keller; Henrietta Leonard Journal: Bipolar Disord Date: 2009-02 Impact factor: 6.744