Literature DB >> 16042274

Hydroxylated PCB metabolites in nonhatched fulmar eggs from the Faroe Islands.

Britta Fängström1, Maria Athanasiadou, Ioannis Athanassiadis, Pál Weihe, Ake Bergman.   

Abstract

Thirty-six polychlorinated biphenylols (OH-PCBs) congeners were characterized in Fulmar (Fulmarus glacialis) eggs collected from the Faroe Islands. The seven most abundant congeners were quantified in 19 samples, and the sigmaOH-PCB concentrations ranged between 0.92 and 4.0 ng g(-1) fresh weight (f.w.). These eggs constitute a part of the traditional diet for at least a part of the population on the Faroe Islands and may contribute to the high levels of these contaminants found in the blood of pregnant Faroese women. Because the metabolites are present in the nonhatched fulmar egg, it is concluded that the OH-PCBs are transferred to the egg before laying. High levels, 3300-18,000 ng g(-1) l.w., of sigmapolychlorinated biphenyls (PCB) were determined in the fulmar eggs, which are a considerable source for human exposure. The high PCB levels are a source for metabolic formation of hydroxylated PCBs.

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Year:  2005        PMID: 16042274

Source DB:  PubMed          Journal:  Ambio        ISSN: 0044-7447            Impact factor:   5.129


  2 in total

Review 1.  Metabolism and metabolites of polychlorinated biphenyls.

Authors:  Fabian A Grimm; Dingfei Hu; Izabela Kania-Korwel; Hans-Joachim Lehmler; Gabriele Ludewig; Keri C Hornbuckle; Michael W Duffel; Åke Bergman; Larry W Robertson
Journal:  Crit Rev Toxicol       Date:  2015-01-28       Impact factor: 5.635

2.  Physicochemical properties of hydroxylated polychlorinated biphenyls aid in predicting their interactions with rat sulfotransferase 1A1 (rSULT1A1).

Authors:  Yungang Liu; Hans-Joachim Lehmler; Larry W Robertson; Michael W Duffel
Journal:  Chem Biol Interact       Date:  2010-12-03       Impact factor: 5.192

  2 in total

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