BACKGROUND: Optical coherence tomography (OCT) is a new imaging method. With a resolution of approximately 10-20 Em, which is approximately 10-fold higher than that of intravascular ultrasound (IVUS). METHODS AND RESULTS: This study compared the coronary intima - media thickness (IMT) and the intimal thickness of 54 coronary arterial segments evaluated by histological examination with the results of OCT and IVUS. There was better agreement in IMT between OCT and histological examination than between IVUS and histological examination (r = 0.95, p < 0.001, mean difference = -0.01+/-0.07 mm for OCT; r = 0.88, p < 0.001, mean difference = -0.03+/-0.10 mm for IVUS). There was good agreement in the intimal thickness between OCT and histological examination (r = 0.98, p < 0.001, mean difference = 0.01+/-0.04 mm). CONCLUSIONS: IMT could be measured more accurately by OCT than IVUS. In addition, the intimal thickness could be evaluated by OCT and correlated well with the histological examination.
BACKGROUND: Optical coherence tomography (OCT) is a new imaging method. With a resolution of approximately 10-20 Em, which is approximately 10-fold higher than that of intravascular ultrasound (IVUS). METHODS AND RESULTS: This study compared the coronary intima - media thickness (IMT) and the intimal thickness of 54 coronary arterial segments evaluated by histological examination with the results of OCT and IVUS. There was better agreement in IMT between OCT and histological examination than between IVUS and histological examination (r = 0.95, p < 0.001, mean difference = -0.01+/-0.07 mm for OCT; r = 0.88, p < 0.001, mean difference = -0.03+/-0.10 mm for IVUS). There was good agreement in the intimal thickness between OCT and histological examination (r = 0.98, p < 0.001, mean difference = 0.01+/-0.04 mm). CONCLUSIONS: IMT could be measured more accurately by OCT than IVUS. In addition, the intimal thickness could be evaluated by OCT and correlated well with the histological examination.
Authors: Emile N Brown; Nicholas S Burris; Zachary N Kon; Michael C Grant; Philip S Brazio; Chenyang Xu; Patrick Laird; Junyen Gu; Seeta Kallam; Pranjal Desai; Robert S Poston Journal: Atherosclerosis Date: 2008-12-14 Impact factor: 5.162
Authors: Luca Di Vito; Francesco Burzotta; Carlo Trani; Giancarlo Pirozzolo; Italo Porto; Giampaolo Niccoli; Antonio Maria Leone; Filippo Crea Journal: Int J Cardiovasc Imaging Date: 2013-10-24 Impact factor: 2.357
Authors: Emile N Brown; Nicholas S Burris; Junyan Gu; Zachary N Kon; Patrick Laird; Seeta Kallam; Cha-Min Tang; Joseph M Schmitt; Robert S Poston Journal: J Biomed Opt Date: 2007 Sep-Oct Impact factor: 3.170
Authors: Nicholas S Burris; Emile N Brown; Michael Grant; Zachary N Kon; Marc Gibber; Junyen Gu; Kimberly Schwartz; Seeta Kallam; Ashish Joshi; Richard Vitali; Robert S Poston Journal: Ann Thorac Surg Date: 2008-04 Impact factor: 4.330