| Literature DB >> 16039691 |
Shinji Ueno1, Mineo Kondo, Makiko Ueno, Kentaro Miyata, Hiroko Terasaki, Yozo Miyake.
Abstract
The purpose of this study was to determine the contribution of different types of retinal neurons to the d-wave of the primate electroretinogram using pharmacological agents. NMDA + TTX was used to suppress inner retinal activity, and APB and PDA to block the activity of the ON- and OFF-pathways, respectively. Results indicated that the inner retinal neurons had a small but certain contribution to the d-wave. The initial rapid phase of the d-wave originates from the activity of the cone OFF-pathway nearly exclusively, and the later slow phase is shaped by the cone photoreceptors. The cone ON-pathway acts in a direction opposite to that of the other components.Entities:
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Year: 2005 PMID： 16039691 DOI： 10.1016/j.visres.2005.05.026
Source DB: PubMed Journal: Vision Res ISSN： 0042-6989 Impact factor: 1.886