Marta I Rendon1, Jorge I Gaviria. 1. Department of Dermatology, Dermatology and Aesthetic Center, Boca Raton, Florida 33486, USA. jimibrain@yahoo.com
Abstract
BACKGROUND: Multiple agents are available for the treatment of hyperpigmentation, a cosmetically important condition seen most often in middle-aged and elderly individuals and resulting from exposure to ultraviolet light, certain drugs or chemicals, or the existence of disease. Many skin-lightening agents cause skin irritation and require months of use before results appear, and some agents are only partly effective. OBJECTIVE: To help dermatologists make an informed decision when choosing a depigmenting agent. METHODS: A review of all depigmenting agents used alone and in combination, including its natural properties and information about safety, efficacy, and optimal dosing. CONCLUSIONS: The speed of efficacy and type and extent of side effects vary greatly among depigmenting agents. Knowing the properties associated with each agent enables a physician to choose a product that will best meet a patient's expectations and minimize adverse reactions.
BACKGROUND: Multiple agents are available for the treatment of hyperpigmentation, a cosmetically important condition seen most often in middle-aged and elderly individuals and resulting from exposure to ultraviolet light, certain drugs or chemicals, or the existence of disease. Many skin-lightening agents cause skin irritation and require months of use before results appear, and some agents are only partly effective. OBJECTIVE: To help dermatologists make an informed decision when choosing a depigmenting agent. METHODS: A review of all depigmenting agents used alone and in combination, including its natural properties and information about safety, efficacy, and optimal dosing. CONCLUSIONS: The speed of efficacy and type and extent of side effects vary greatly among depigmenting agents. Knowing the properties associated with each agent enables a physician to choose a product that will best meet a patient's expectations and minimize adverse reactions.
Authors: Lucia Steenkamp; Kgama Mathiba; Paul Steenkamp; Vuyisile Phehane; Robin Mitra; Steven Heggie; Dean Brady Journal: J Ind Microbiol Biotechnol Date: 2012-02-29 Impact factor: 3.346
Authors: Su Jin Hwang; Su Hwan Kim; Woo-Young Seo; Yelin Jeong; Min Cheol Shin; Dongryeol Ryu; Sang Bae Lee; Young Jin Choi; KyeongJin Kim Journal: BMB Rep Date: 2021-06 Impact factor: 4.778