PURPOSE: To investigate the diffusion tensor properties of the human optic nerve in vivo using a non-Carr-Purcell-Meiboom-Gill (CPMG) fast spin echo (FSE) sequence. MATERIALS AND METHODS: This non-CPMG FSE sequence, which is based on a quadratic phase modulation of the refocusing pulses, allows diffusion measures to be acquired with full signal and without artifacts from geometric distortions due to magnetic field inhomogeneities, which are among the main problems encountered in the orbital area. RESULTS: Good-quality images were obtained at a resolution of 0.94 x 0.94 x 3 mm. The mean diffusivity (MD) and fractional anisotropy (FA) were respectively 1.1 +/- 0.2 x 10(-3) mm(2)/second and 0.49 +/- 0.06, reflecting the optic nerve anisotropy. CONCLUSION: This non-CPMG-FSE sequence provides reliable diffusion-weighted images of the human optic nerve. This approach could potentially improve the diagnosis and management of optic nerve diseases or compression, such as optic neuritis, orbit tumors, and muscle hypertrophy. (c) 2005 Wiley-Liss, Inc.
PURPOSE: To investigate the diffusion tensor properties of the human optic nerve in vivo using a non-Carr-Purcell-Meiboom-Gill (CPMG) fast spin echo (FSE) sequence. MATERIALS AND METHODS: This non-CPMG FSE sequence, which is based on a quadratic phase modulation of the refocusing pulses, allows diffusion measures to be acquired with full signal and without artifacts from geometric distortions due to magnetic field inhomogeneities, which are among the main problems encountered in the orbital area. RESULTS: Good-quality images were obtained at a resolution of 0.94 x 0.94 x 3 mm. The mean diffusivity (MD) and fractional anisotropy (FA) were respectively 1.1 +/- 0.2 x 10(-3) mm(2)/second and 0.49 +/- 0.06, reflecting the optic nerve anisotropy. CONCLUSION: This non-CPMG-FSE sequence provides reliable diffusion-weighted images of the human optic nerve. This approach could potentially improve the diagnosis and management of optic nerve diseases or compression, such as optic neuritis, orbit tumors, and muscle hypertrophy. (c) 2005 Wiley-Liss, Inc.
Authors: Ha-Kyu Jeong; Blake E Dewey; Jane A T Hirtle; Patrick Lavin; Subramaniam Sriram; Siddharama Pawate; John C Gore; Adam W Anderson; Hakmook Kang; Seth A Smith Journal: Magn Reson Med Date: 2014-09-26 Impact factor: 4.668
Authors: Eric K Gibbons; Patrick Le Roux; Shreyas S Vasanawala; John M Pauly; Adam B Kerr Journal: IEEE Trans Med Imaging Date: 2017-08-17 Impact factor: 10.048
Authors: R T Naismith; J Xu; N T Tutlam; A Snyder; T Benzinger; J Shimony; J Shepherd; K Trinkaus; A H Cross; S-K Song Journal: Neurology Date: 2008-12-10 Impact factor: 9.910