Literature DB >> 16013902

Severe obsessive-compulsive disorder with and without comorbid hair pulling: comparisons and clinical implications.

S Evelyn Stewart1, Michael A Jenike, Nancy J Keuthen.   

Abstract

OBJECTIVE: Chronic hair pulling and trichotillomania are putative obsessive-compulsive spectrum disorders. This study determined the prevalence of hair pulling in an inpatient obsessive-compulsive disorder (OCD) population and compared clinical characteristics and treatment response between subgroups with and without comorbid hair pulling.
METHOD: Patients with severe DSM-IV-diagnosed OCD (N = 154) who were consecutively admitted to an OCD residential treatment facility between August 2000 and July 2003 were included. Clinician-rated (Yale-Brown Obsessive Compulsive Scale) and patient-rated (Massachusetts General Hospital Hairpulling Scale, Beck Depression Inventory, and Posttraumatic Diagnostic Scale) measures were administered at index evaluation. OCD patients with and without moderate to severe hair pulling were statistically compared on clinical and treatment characteristics and treatment response.
RESULTS: Of the OCD subjects, 18.8% (N = 29) endorsed any hair pulling, 15.6% (N = 24) had moderate to severe hair pulling, and 7.8% (N = 12) had severe hair pulling comparable to that of a specialty trichotillomania clinic population. OCD patients with moderate to severe hair pulling were more likely to be women (p < .001), endorse > 1 comorbid tic (p < .05), and have earlier-onset OCD (p = .001). This cohort also had fewer contamination obsessions (p = .04) and checking compulsions (p = .04) and was more likely to be receiving stimulant (p = .006) or venlafaxine (p = .02) medication than those patients without hair pulling. Posttraumatic Diagnostic Scale scores were nearly significantly higher in the OCD + hair pulling group (p = .08). OCD treatment response was unaffected by the presence of comorbid hair pulling.
CONCLUSION: Hair pulling is a highly common comorbidity in severe OCD. Women and early-onset OCD patients appear to be more vulnerable to comorbid hair pulling. OCD sufferers with comorbid hair pulling also exhibit an increased risk for tics and may present with different OCD symptomatology.

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Year:  2005        PMID: 16013902     DOI: 10.4088/jcp.v66n0709

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


  8 in total

Review 1.  Obsessive-compulsive disorder: a review of the diagnostic criteria and possible subtypes and dimensional specifiers for DSM-V.

Authors:  James F Leckman; Damiaan Denys; H Blair Simpson; David Mataix-Cols; Eric Hollander; Sanjaya Saxena; Euripedes C Miguel; Scott L Rauch; Wayne K Goodman; Katharine A Phillips; Dan J Stein
Journal:  Depress Anxiety       Date:  2010-06       Impact factor: 6.505

2.  Clinical significance of psychiatric comorbidity in children and adolescents with obsessive-compulsive disorder: subtyping a complex disorder.

Authors:  A E Ortiz; A Morer; E Moreno; M T Plana; C Cordovilla; L Lázaro
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2015-09-15       Impact factor: 5.270

3.  Symptom profiles in pediatric obsessive-compulsive disorder (OCD): the effects of comorbid grooming conditions.

Authors:  Christopher A Flessner; Noah Berman; Abbe Garcia; Jennifer B Freeman; Henrietta L Leonard
Journal:  J Anxiety Disord       Date:  2009-03-11

Review 4.  Assessing the validity of current mouse genetic models of obsessive-compulsive disorder.

Authors:  Li Wang; Helen B Simpson; Stephanie C Dulawa
Journal:  Behav Pharmacol       Date:  2009-03       Impact factor: 2.293

5.  A comparison of symptom dimensions for obsessive compulsive disorder and obsessive compulsive-related disorders.

Authors:  Derya Say Öcal; Kadir Özdel; Yasir Şafak; Yasemin Kekilli Karnaz; Cebrail Kısa
Journal:  PLoS One       Date:  2019-07-05       Impact factor: 3.240

Review 6.  Trichotillomania is more related to Tourette disorder than to obsessive-compulsive disorder.

Authors:  Hugues Lamothe; Jean-Marc Baleyte; Luc Mallet; Antoine Pelissolo
Journal:  Braz J Psychiatry       Date:  2020 Jan-Feb       Impact factor: 2.697

Review 7.  Symptom dimensions and subtypes of obsessive-compulsive disorder: a developmental perspective.

Authors:  James F Leckman; Michael H Bloch; Robert A King
Journal:  Dialogues Clin Neurosci       Date:  2009       Impact factor: 5.986

8.  Serum Proteomic Profiling of Obsessive-Compulsive Disorder, Washing Subtype: A Preliminary Study.

Authors:  Mona Zamanian-Azodi; Mostafa Rezaei-Tavirani; Naser Nejadi; Afsaneh Arefi Oskouie; Faird Zayeri; Mostafa Hamdieh; Akram Safaei; Majid Rezaei-Tavirani; Alireza Ahmadzadeh; Alireza Amouzandeh-Nobaveh; Farshad Okhovatian
Journal:  Basic Clin Neurosci       Date:  2017 Jul-Aug
  8 in total

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