Literature DB >> 16010346

2-Pyrone natural products and mimetics: isolation, characterisation and biological activity.

Gerard P McGlacken1, Ian J S Fairlamb.   

Abstract

The review summarises natural products containing the 2-pyrone moiety. An emphasis has been placed upon the biological activity associated with 2-pyrones, particularly with respect to potential therapeutic or anti-microbial agents. Where appropriate, non-natural 2-pyrone analogues are discussed, particularly those derived from natural product lead compounds.

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Year:  2005        PMID： 16010346     DOI： 10.1039/b416651p

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  39 in total

1.  Production and genetic improvement of a novel antimycotic agent, saadamycin, against dermatophytes and other clinical fungi from endophytic Streptomyces sp. Hedaya48.

Authors:  Mervat M A El-Gendy; Ahmed M A El-Bondkly
Journal:  J Ind Microbiol Biotechnol       Date:  2010-05-12       Impact factor: 3.346

2.  Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers.

Authors:  Stephen T McCracken; Marcel Kaiser; Helena I Boshoff; Peter D W Boyd; Brent R Copp
Journal:  Bioorg Med Chem       Date:  2012-01-02       Impact factor: 3.641

3.  Germicidins H-J from Streptomyces sp. CB00361.

Authors:  Ming Ma; Mostafa E Rateb; Dong Yang; Jeffrey D Rudolf; Xiangcheng Zhu; Yong Huang; Li-Xing Zhao; Yi Jiang; Yanwen Duan; Ben Shen
Journal:  J Antibiot (Tokyo)       Date:  2016-08-10       Impact factor: 2.649

4.  Gibepyrone Biosynthesis in the Rice Pathogen Fusarium fujikuroi Is Facilitated by a Small Polyketide Synthase Gene Cluster.

Authors:  Slavica Janevska; Birgit Arndt; Eva-Maria Niehaus; Immo Burkhardt; Sarah M Rösler; Nelson L Brock; Hans-Ulrich Humpf; Jeroen S Dickschat; Bettina Tudzynski
Journal:  J Biol Chem       Date:  2016-11-17       Impact factor: 5.157

Review 5.  Alkynoates as Versatile and Powerful Chemical Tools for the Rapid Assembly of Diverse Heterocycles under Transition-Metal Catalysis: Recent Developments and Challenges.

Authors:  Imtiaz Khan; Aliya Ibrar; Sumera Zaib
Journal:  Top Curr Chem (Cham)       Date:  2021-01-05

6.  Anti-leukemic effect of 2-pyrone derivatives via MAPK and PI3 kinase pathways.

Authors:  Jin Sun Yoon; Young Woong Won; Seo Ju Kim; Suk Joong Oh; Eun Shil Kim; Byoung Kook Kim; Cheon Gyu Cho; Jung Hye Choi; Byeong Bae Park; Min Ho Lee; Young Yiul Lee
Journal:  Invest New Drugs       Date:  2012-04-19       Impact factor: 3.850

7.  Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues.

Authors:  Martina Werneburg; Benjamin Busch; Jing He; Martin E A Richter; Longkuan Xiang; Bradley S Moore; Martin Roth; Hans-Martin Dahse; Christian Hertweck
Journal:  J Am Chem Soc       Date:  2010-08-04       Impact factor: 15.419

8.  Antibacterial neurymenolides from the Fijian red alga Neurymenia fraxinifolia.

Authors:  E Paige Stout; Adam P Hasemeyer; Amy L Lane; Theresa M Davenport; Sebastian Engel; Mark E Hay; Craig R Fairchild; Jacques Prudhomme; Karine Le Roch; William Aalbersberg; Julia Kubanek
Journal:  Org Lett       Date:  2009-01-01       Impact factor: 6.005

9.  Pd/C-mediated synthesis of α-pyrone fused with a five-membered nitrogen heteroaryl ring: a new route to pyrano[4,3-c]pyrazol-4(1H)-ones.

Authors:  Dhilli Rao Gorja; Venkateswara Rao Batchu; Ashok Ettam; Manojit Pal
Journal:  Beilstein J Org Chem       Date:  2009-11-11       Impact factor: 2.883

Review 10.  Astonishing diversity of natural surfactants: 7. Biologically active hemi- and monoterpenoid glycosides.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2006-01       Impact factor: 1.880
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