Literature DB >> 16009385

Transcription-coupled repair and premature ageing.

J O Andressoo1, J H J Hoeijmakers.   

Abstract

During the past decades, several cellular pathways have been discovered to be connected with the ageing process. These pathways, which either suppress or enhance the ageing process, include regulation of the insulin/growth hormone axis, pathways involved with caloric restriction, ROS metabolism and DNA repair. In this review, we will provide a comprehensive overview of cancer and/or accelerated ageing pathologies associated with defects in the multi-step nucleotide excision repair pathway. Moreover, we will discuss evidence suggesting that there is a causative link between transcription-coupled repair and ageing.

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Year:  2005        PMID： 16009385     DOI： 10.1016/j.mrfmmm.2005.04.004

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  23 in total

1.  RPA and ATR link transcriptional stress to p53.

Authors:  Frederick A Derheimer; Heather M O'Hagan; Heather M Krueger; Sheela Hanasoge; Michelle T Paulsen; Mats Ljungman
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-06       Impact factor: 11.205

2.  Structure and Mechanisms of SF1 DNA Helicases.

Authors:  Kevin D Raney; Alicia K Byrd; Suja Aarattuthodiyil
Journal:  Adv Exp Med Biol       Date:  2013       Impact factor: 2.622

3.  Nucleotide excision DNA repair is associated with age-related vascular dysfunction.

Authors:  Matej Durik; Maryam Kavousi; Ingrid van der Pluijm; Aaron Isaacs; Caroline Cheng; Koen Verdonk; Annemarieke E Loot; Hisko Oeseburg; Usha Musterd Bhaggoe; Frank Leijten; Richard van Veghel; René de Vries; Goran Rudez; Renata Brandt; Yanto R Ridwan; Elza D van Deel; Martine de Boer; Dennie Tempel; Ingrid Fleming; Gary F Mitchell; Germaine C Verwoert; Kirill V Tarasov; Andre G Uitterlinden; Albert Hofman; Henricus J Duckers; Cornelia M van Duijn; Ben A Oostra; Jacqueline C M Witteman; Dirk J Duncker; A H Jan Danser; Jan H Hoeijmakers; Anton J M Roks
Journal:  Circulation       Date:  2012-06-15       Impact factor: 29.690

Review 4.  Regulation of active genome integrity and expression by Rad26p.

Authors:  Shivani Malik; Sukesh R Bhaumik
Journal:  Nucleus       Date:  2014-10-31       Impact factor: 4.197

5.  Newly identified CHO ERCC3/XPB mutations and phenotype characterization.

Authors:  Ivana Rybanská; Ján Gursky; Miriam Fasková; Edmund P Salazar; Erika Kimlícková-Polakovicová; Karol Kleibl; Larry H Thompson; Miroslav Pirsel
Journal:  Mutagenesis       Date:  2009-11-25       Impact factor: 3.000

6.  Transcriptional bypass of bulky DNA lesions causes new mutant RNA transcripts in human cells.

Authors:  Cheryl Marietta; Philip J Brooks
Journal:  EMBO Rep       Date:  2007-03-16       Impact factor: 8.807

7.  An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.

Authors:  Jaan-Olle Andressoo; Geert Weeda; Jan de Wit; James R Mitchell; Rudolf B Beems; Harry van Steeg; Gijsbertus T J van der Horst; Jan H Hoeijmakers
Journal:  Mol Cell Biol       Date:  2008-12-29       Impact factor: 4.272

8.  Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation.

Authors:  Sarah Sertic; Sara Pizzi; Ross Cloney; Alan R Lehmann; Federica Marini; Paolo Plevani; Marco Muzi-Falconi
Journal:  Proc Natl Acad Sci U S A       Date:  2011-08-01       Impact factor: 11.205

9.  Bone fragility and decline in stem cells in prematurely aging DNA repair deficient trichothiodystrophy mice.

Authors:  Karin E M Diderich; Claudia Nicolaije; Matthias Priemel; Jan H Waarsing; Judd S Day; Renata M C Brandt; Arndt F Schilling; Sander M Botter; Harrie Weinans; Gijsbertus T J van der Horst; Jan H J Hoeijmakers; Johannes P T M van Leeuwen
Journal:  Age (Dordr)       Date:  2011-08-04

Review 10.  RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination.

Authors:  Evert-Jan Uringa; Jillian L Youds; Kathleen Lisaingo; Peter M Lansdorp; Simon J Boulton
Journal:  Nucleic Acids Res       Date:  2010-11-18       Impact factor: 16.971
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