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Literature DB >> 16003804

Synthesis and degradation of nucleic Acid components by formamide and cosmic dust analogues.

Raffaele Saladino¹, Claudia Crestini, Veronica Neri, John R Brucato, Luigi Colangeli, Fabiana Ciciriello, Ernesto Di Mauro, Giovanna Costanzo.

Abstract

We show the unprecedented one-pot synthesis of a large suite of pyrimidines (including cytosine and uracil) and purines from formamide in the presence of cosmic-dust analogues (CDAs) of olivines. Since the major problem in the origin of informational macromolecules is the instability of their precursors, we also investigate the stabilizing effect of CDAs on the intrinsic instability of oligonucleotides in formamide.

Entities: Chemical

Mesh：

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Year: 2005 PMID： 16003804 DOI： 10.1002/cbic.200500035

Source DB: PubMed Journal: Chembiochem ISSN： 1439-4227 Impact factor: 3.164

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Cited

11 in total

1. The effects of borate minerals on the synthesis of nucleic acid bases, amino acids and biogenic carboxylic acids from formamide.

Authors: Raffaele Saladino; Maurizio Barontini; Cristina Cossetti; Ernesto Di Mauro; Claudia Crestini
Journal: Orig Life Evol Biosph Date: 2011-03-19 Impact factor: 1.950

2. Synthesis of Nucleic Acid Bases by Metal Ferrite Nanoparticles from a Single Carbon Atom Precursor Molecule: Formamide.

Authors: Mohammad Asif Iqubal; Rachana Sharma; Sohan Jheeta
Journal: Orig Life Evol Biosph Date: 2019-08-23 Impact factor: 1.950

3. About a formamide-based origin of informational polymers: syntheses of nucleobases and favourable thermodynamic niches for early polymers.

Authors: Raffaele Saladino; Claudia Crestini; Fabiana Ciciriello; Giovanna Costanzo; Ernesto Di Mauro
Journal: Orig Life Evol Biosph Date: 2006-12 Impact factor: 1.950

4. Cryogenic synthesis of molecules of astrobiological interest: catalytic role of cosmic dust analogues.

Authors: J R Brucato; G Strazzulla; G A Baratta; A Rotundi; L Colangeli
Journal: Orig Life Evol Biosph Date: 2006-12 Impact factor: 1.950

5. Formamide as the main building block in the origin of nucleic acids.

Authors: Giovanna Costanzo; Raffaele Saladino; Claudia Crestini; Fabiana Ciciriello; Ernesto Di Mauro
Journal: BMC Evol Biol Date: 2007-08-16 Impact factor: 3.260

6. Thermodynamic potential for the abiotic synthesis of adenine, cytosine, guanine, thymine, uracil, ribose, and deoxyribose in hydrothermal systems.

Authors: Douglas E LaRowe; Pierre Regnier
Journal: Orig Life Evol Biosph Date: 2008-06-24 Impact factor: 1.950

Synthesis and degradation of nucleic Acid components by formamide and cosmic dust analogues.

1. The effects of borate minerals on the synthesis of nucleic acid bases, amino acids and biogenic carboxylic acids from formamide.

2. Synthesis of Nucleic Acid Bases by Metal Ferrite Nanoparticles from a Single Carbon Atom Precursor Molecule: Formamide.

3. About a formamide-based origin of informational polymers: syntheses of nucleobases and favourable thermodynamic niches for early polymers.

4. Cryogenic synthesis of molecules of astrobiological interest: catalytic role of cosmic dust analogues.

5. Formamide as the main building block in the origin of nucleic acids.

6. Thermodynamic potential for the abiotic synthesis of adenine, cytosine, guanine, thymine, uracil, ribose, and deoxyribose in hydrothermal systems.

7. Monitoring the Reactivity of Formamide on Amorphous SiO₂ by In-Situ UV-Raman Spectroscopy and DFT Modeling.

Review 8. A Universal Geochemical Scenario for Formamide Condensation and Prebiotic Chemistry.

Review 9. Astrochemistry and Astrobiology: Materials Sciencein Wonderland?

10. Dispersion corrected DFT approaches for anharmonic vibrational frequency calculations: nucleobases and their dimers.