| Literature DB >> 1600038 |
G O Young1, N Stemmet, A Lastovica, E L van der Merwe, J A Louw, I M Modlin, I N Marks.
Abstract
The effect of Helicobacter pylori lipopolysaccharide on guinea pig gastric mucosal pepsinogen secretion has been examined using an Ussing chamber technique. Luminal addition of H. pylori lipopolysaccharide resulted in a fifty-fold stimulation of pepsinogen secretion compared to a twelve-fold increase with E. coli lipopolysaccharide. Electron microscopy showed marked degranulation of zymogen granules but no evidence of chief cell disruption.Entities:
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Year: 1992 PMID： 1600038 DOI： 10.1111/j.1365-2036.1992.tb00260.x
Source DB: PubMed Journal: Aliment Pharmacol Ther ISSN： 0269-2813 Impact factor: 8.171