Literature DB >> 15992124

Ropinirole in the treatment of Parkinson's disease.

T A Zesiewicz1, R A Hauser.   

Abstract

In this review, the pharmacokinetics, safety and tolerability, and clinical efficacy of ropinirole (Requip), a non-ergoline dopamine agonist approved for use in the treatment of Parkinson's disease (PD) are examined. A summary of preclinical and clinical studies is presented. Ropinirole is safe and efficacious as monotherapy in the treatment of early PD and as an adjunct to levodopa in more advanced cases.

Entities:  

Year:  1999        PMID: 15992124     DOI: 10.1517/13543784.8.5.697

Source DB:  PubMed          Journal:  Expert Opin Investig Drugs        ISSN: 1354-3784            Impact factor:   6.206


  3 in total

Review 1.  Ropinirole: a review of its use in the management of Parkinson's disease.

Authors:  A J Matheson; C M Spencer
Journal:  Drugs       Date:  2000-07       Impact factor: 9.546

Review 2.  Clinical pharmacokinetics of ropinirole.

Authors:  C M Kaye; B Nicholls
Journal:  Clin Pharmacokinet       Date:  2000-10       Impact factor: 6.447

3.  Construction of a spirooxindole amide library through nitrile hydrozirconation-acylation-cyclization cascade.

Authors:  Matthew G LaPorte; Sammi Tsegay; Ki Bum Hong; Chunliang Lu; Cheng Fang; Lirong Wang; Xiang-Qun Xie; Paul E Floreancig
Journal:  ACS Comb Sci       Date:  2013-06-26       Impact factor: 3.784

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.