Literature DB >> 15988249

Furlow palatoplasty for management of velopharyngeal insufficiency: a prospective study of 148 consecutive patients.

Jonathan A Perkins1, Charlotte W Lewis, Joseph S Gruss, Linda E Eblen, Kathleen C Y Sie.   

Abstract

BACKGROUND: The objectives of the study were to describe speech outcomes in a large series of patients undergoing Furlow palatoplasty for management of velopharyngeal insufficiency and to test whether preoperative velopharyngeal gap size and other patient characteristics significantly affect those outcomes.
METHODS: Data collected included age at the time of surgery, surgeon, type of cleft, syndrome diagnosis, preoperative velopharyngeal gap size as determined by videonasendoscopy, and preoperative and postoperative perceptual speech assessments. Descriptive statistics were generated and ordinal logistic regression on the outcome variable, postoperative velopharyngeal insufficiency severity score, was performed.
RESULTS: In this series of 154 patients, 148 had complete perceptual speech data. Of these 148 patients, 72 percent had improvement in velopharyngeal insufficiency severity after the procedure and 56 percent had complete resolution of velopharyngeal insufficiency. Postoperative insufficiency was scored as none or minimal (i.e., resolution) in 38 of 52 patients (73 percent) with a small preoperative velopharyngeal gap, 26 of 51 patients (51 percent) with a moderate preoperative gap, and four of 21 patients (19 percent) with a large preoperative gap. Preoperative velopharyngeal gap size was significantly associated (p < 0.0001) with postoperative insufficiency on ordinal multivariate logistic regression after controlling for preoperative insufficiency and other covariates. There was not a significant association between syndrome diagnosis, age at Furlow palatoplasty (younger than 5 years versus older), gender, surgeon, or presence of submucous cleft palate and postoperative speech outcome, in either the unadjusted or adjusted analyses.
CONCLUSIONS: Preoperative velopharyngeal gap size, as determined with nasendoscopy, was significantly associated with postoperative velopharyngeal insufficiency severity after Furlow palatoplasty. Small gap size is associated with a greater likelihood of resolution.

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Mesh:

Year:  2005        PMID: 15988249     DOI: 10.1097/01.prs.0000169694.29082.69

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  8 in total

1.  Velopharyngeal dysfunction.

Authors:  Albert S Woo
Journal:  Semin Plast Surg       Date:  2012-11       Impact factor: 2.314

2.  The Effectiveness of Palate Re-Repair for Treating Velopharyngeal Insufficiency: A Systematic Review and Meta-Analysis.

Authors:  Nicole M Kurnik; Erica M Weidler; Kari M Lien; Kelly N Cordero; Jessica L Williams; M'hamed Temkit; Stephen P Beals; Davinder J Singh; Thomas J Sitzman
Journal:  Cleft Palate Craniofac J       Date:  2020-02-19

3.  Influence of preoperative velar closing ratio and lateral wall movement on outcomes of Furlow palatoplasty for velopharyngeal incompetence.

Authors:  Arshad R Muzaffar; Gale Rice; Bradley Hubbard; Elizabeth Killion
Journal:  Plast Surg (Oakv)       Date:  2014       Impact factor: 0.947

4.  The effect of cleft palate repair on contractile properties of single permeabilized muscle fibers from congenitally cleft goat palates.

Authors:  Michael C Hanes; Jeffrey Weinzweig; Kip E Panter; W Thomas McClellan; Stefanie A Caterson; Steven R Buchman; John A Faulkner; Deborah Yu; Paul S Cederna; Lisa M Larkin
Journal:  Ann Plast Surg       Date:  2008-02       Impact factor: 1.539

Review 5.  In search of the optimal surgical treatment for velopharyngeal dysfunction in 22q11.2 deletion syndrome: a systematic review.

Authors:  Nicole E Spruijt; Judith Reijmanhinze; Greet Hens; Vincent Vander Poorten; Aebele B Mink van der Molen
Journal:  PLoS One       Date:  2012-03-28       Impact factor: 3.240

6.  A Comparative Study to Evaluate the Functional Effect of Unilateral Uvuloplasty after Primary Palatoplasty.

Authors:  Percy Rossell-Perry; Claudia Olivencia-Flores; Arquímedes M Gavino-Gutierrez; Evelyn Caceres-Nano; Omar Cotrina-Rabanal
Journal:  Plast Reconstr Surg Glob Open       Date:  2015-07-08

7.  Velo-pharyngeal dysfunction: Evaluation and management.

Authors:  Jeffrey L Marsh
Journal:  Indian J Plast Surg       Date:  2009-10

8.  Buccinator myomucosal flap for the treatment of velopharyngeal insufficiency in patients with cleft palate and/or lip.

Authors:  Rafael Denadai; Anelise Sabbag; Cassio Eduardo Raposo Amaral; João Carlos Pereira Filho; Mirian Hideko Nagae; Cesar Augusto Raposo Amaral
Journal:  Braz J Otorhinolaryngol       Date:  2017-09-12
  8 in total

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