Literature DB >> 159864

Rabbit anti-EL4 serum. A reagent with specificity for a population of murine suppressor cells.

L Al-Sakkaf, A Cooke, P Hutchings, B Jones.   

Abstract

Antisera against the C57B1 (H-2b) mouse lymphoma, EL4 were prepared in rabbits. After absorption with mouse liver, red cells and thymocytes the antisera appeared to be cytotoxic for a subpopulation of peripheral T cells. The absorbed antisera blocked the immunosuppressor function of Con A-stimulated splenic lymphocytes, but was unreactive against Con A-stimulated and allogeneically primed cytotoxic cells, or helper T cells. Consequently, heteroantiserum against EL4 may provide a useful reagent for the differentiation of cytotoxic from suppressor T-cell subsets.

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Year:  1979        PMID： 159864      PMCID： PMC1457945     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  18 in total

1.  Age-dependent changes in the relative affinity of anti-dinitrophenyl antibodies in mice.

Authors:  S Marshall-Clarke; J H Playfair
Journal:  Immunology       Date:  1975-09       Impact factor: 7.397

2.  Subclasses of T cells with different sensitivities to cytotoxic antibody in the presence of anesthetics.

Authors:  S K Lee; J Singh; R B Taylor
Journal:  Eur J Immunol       Date:  1975-04       Impact factor: 5.532

3.  Ly-A and Ly-B: two systems of lymphocyte isoantigens in the mouse.

Authors:  E A Boyse; M Miyazawa; T Aoki; L J Old
Journal:  Proc R Soc Lond B Biol Sci       Date:  1968-06-11

4.  Allograft cytotoxicity. Two populations of effector cell detectable by cytolytic and cytostatic assays in vitro.

Authors:  B Jones; T C Jones; I M Roitt
Journal:  Immunology       Date:  1977-04       Impact factor: 7.397

5.  Fractionation of cytotoxic T lymphoblasts on Ficoll gradients by velocity sedimentation.

Authors:  A H Greenberg
Journal:  Eur J Immunol       Date:  1973-12       Impact factor: 5.532

6.  Role of thymus-derived lymphocytes in the secondary humoral immune response in mice.

Authors:  M C Raff
Journal:  Nature       Date:  1970-06-27       Impact factor: 49.962

Review 7.  The cellular basis of immunological responses. A synthesis of some current views.

Authors:  I M Roitt; M F Greaves; G Torrigiani; J Brostoff; J H Playfair
Journal:  Lancet       Date:  1969-08-16       Impact factor: 79.321

8.  Immunosuppressive activity of a subline of the mouse EL-4 lymphoma. Evidence for minute virus of mice causing the inhibition.

Authors:  G D Bonnard; E K Manders; D A Campbell; R B Herberman; M J Collins
Journal:  J Exp Med       Date:  1976-01-01       Impact factor: 14.307

9.  Immunoregulatory circuits among T-cell sets. I. T-helper cells induce other T-cell sets to exert feedback inhibition.

Authors:  D D Eardley; J Hugenberger; L McVay-Boudreau; F W Shen; R K Gershon; H Cantor
Journal:  J Exp Med       Date:  1978-04-01       Impact factor: 14.307

10.  Cellular mediators of anti-Listeria immunity as an enlarged population of short lived, replicating T cells. Kinetics of their production.

Authors:  R J North
Journal:  J Exp Med       Date:  1973-08-01       Impact factor: 14.307
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  2 in total

1.  Direct staining of mouse T lymphoblasts with fluoresceinated Vicia villosa lectin.

Authors:  I Lang; J P Banga; A M Varey; H Gunn; A Cooke; I M Roitt
Journal:  Immunology       Date:  1982-08       Impact factor: 7.397

2.  Rabbit anti-EL4 serum. A reagent which discriminates between murine cytotoxic and suppressor cells.

Authors:  L Al-Sakkaf; A Cooke; L Heppel; P Hutchings; B Jones
Journal:  Immunology       Date:  1979-11       Impact factor: 7.397
  2 in total

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