Literature DB >> 15981414

Fumaquinone, a new prenylated naphthoquinone from Streptomyces fumanus.

Romila D Charan1, Gerhard Schlingmann, Valerie S Bernan, Xidong Feng, Guy T Carter.   

Abstract

A new prenylated naphthoquinone antibiotic, fumaquinone (5,7-dihydroxy-2-methoxy-3-methyl-6-(3-methyl-but-2-enyl)[1,4]naphthoquinone) was isolated from cultures of Streptomyces fumanus (LL-F42248). Its chemical structure was determined primarily by NMR spectroscopy. Preliminary feeding experiments indicated the naphthoquinone is of polyketide origin, while the O-methyl and aromatic C-methyl groups are derived from methionine.

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Year:  2005        PMID: 15981414     DOI: 10.1038/ja.2005.32

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


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  3 in total

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