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Literature DB >> 15981022

Distinct effects of PPARgamma insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells.

Hiroshi Kawaguchi¹, Toru Akune, Masayuki Yamaguchi, Shinsuke Ohba, Naoshi Ogata, Ung-il Chung, Naoto Kubota, Yasuo Terauchi, Takashi Kadowaki, Kozo Nakamura.

Abstract

Entities: Disease Gene

Mesh：

Substances：
PPAR gamma

Year: 2005 PMID： 15981022 DOI： 10.1007/s00774-005-0599-2

Source DB: PubMed Journal: J Bone Miner Metab ISSN： 0914-8779 Impact factor: 2.626

× No keyword cloud information.

36 in total

Review 1. Insights into insulin resistance and type 2 diabetes from knockout mouse models.

Authors: T Kadowaki
Journal: J Clin Invest Date: 2000-08 Impact factor: 14.808

2. Serum levels of insulin-like growth factor (IGF) I, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures.

Authors: T Sugimoto; K Nishiyama; F Kuribayashi; K Chihara
Journal: J Bone Miner Res Date: 1997-08 Impact factor: 6.741

3. Leptin regulates bone formation via the sympathetic nervous system.

Authors: Shu Takeda; Florent Elefteriou; Regis Levasseur; Xiuyun Liu; Liping Zhao; Keith L Parker; Dawna Armstrong; Patricia Ducy; Gerard Karsenty
Journal: Cell Date: 2002-11-01 Impact factor: 41.582

4. Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover.

Authors: N Ogata; D Chikazu; N Kubota; Y Terauchi; K Tobe; Y Azuma; T Ohta; T Kadowaki; K Nakamura; H Kawaguchi
Journal: J Clin Invest Date: 2000-04 Impact factor: 14.808

5. Adiponectin as a novel determinant of bone mineral density and visceral fat.

Authors: L Lenchik; T C Register; F C Hsu; K Lohman; B J Nicklas; B I Freedman; C D Langefeld; J J Carr; D W Bowden
Journal: Bone Date: 2003-10 Impact factor: 4.398

Review 6. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men.

Authors: B L Riggs; S Khosla; L J Melton
Journal: J Bone Miner Res Date: 1998-05 Impact factor: 6.741

7. Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: a comparative histomorphometric study.

Authors: R Burkhardt; G Kettner; W Böhm; M Schmidmeier; R Schlag; B Frisch; B Mallmann; W Eisenmenger; T Gilg
Journal: Bone Date: 1987 Impact factor: 4.398

8. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor.

Authors: P Tontonoz; E Hu; B M Spiegelman
Journal: Cell Date: 1994-12-30 Impact factor: 41.582

9. Adipocytic cells cultured from marrow have osteogenic potential.

Authors: J H Bennett; C J Joyner; J T Triffitt; M E Owen
Journal: J Cell Sci Date: 1991-05 Impact factor: 5.285

10. Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction.

Authors: K Kobayashi; N Takahashi; E Jimi; N Udagawa; M Takami; S Kotake; N Nakagawa; M Kinosaki; K Yamaguchi; N Shima; H Yasuda; T Morinaga; K Higashio; T J Martin; T Suda
Journal: J Exp Med Date: 2000-01-17 Impact factor: 14.307

31 in total

10. Bone marrow stromal cell lines having high potential for osteoclast-supporting activity express PPARgamma1 and show high potential for differentiation into adipocytes.

Authors: Katsuhisa Takagi; Akira Kudo
Journal: J Bone Miner Metab Date: 2008-01-10 Impact factor: 2.626

Distinct effects of PPARgamma insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells.

Review 1. Insights into insulin resistance and type 2 diabetes from knockout mouse models.

2. Serum levels of insulin-like growth factor (IGF) I, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures.

3. Leptin regulates bone formation via the sympathetic nervous system.

4. Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover.

5. Adiponectin as a novel determinant of bone mineral density and visceral fat.

Review 6. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men.

7. Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: a comparative histomorphometric study.

8. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor.

9. Adipocytic cells cultured from marrow have osteogenic potential.

10. Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction.

1. Pathophysiological role of enhanced bone marrow adipogenesis in diabetic complications.

Review 2. Diabetes pharmacotherapy and effects on the musculoskeletal system.

Review 3. The interrelationship between bone and fat: from cellular see-saw to endocrine reciprocity.

Review 4. Calcific aortic valve stenosis: methods, models, and mechanisms.

Review 5. PPARgamma in human and mouse physiology.

6. Regulation of neural crest cell fate by the retinoic acid and Pparg signalling pathways.

7. Pioglitazone attenuates valvular calcification induced by hypercholesterolemia.

Review 8. Risk of fractures with glitazones: a critical review of the evidence to date.

9. Upregulation of Adipogenesis and Chondrogenesis in MSC Serum-Free Culture.

10. Bone marrow stromal cell lines having high potential for osteoclast-supporting activity express PPARgamma1 and show high potential for differentiation into adipocytes.