Literature DB >> 15980397

Interaction of the plasmid-encoded quinolone resistance protein QnrA with Escherichia coli topoisomerase IV.

John H Tran1, George A Jacoby, David C Hooper.   

Abstract

Purified QnrA blocked ciprofloxacin inhibition of topoisomerase IV, just as QnrA was previously found to prevent quinolone inhibition of DNA gyrase. With a gel displacement assay, tagged QnrA was shown to bind to topoisomerase IV and its subunits in a reaction that did not depend on the presence of DNA, quinolone, or ATP.

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Year:  2005        PMID: 15980397      PMCID: PMC1168640          DOI: 10.1128/AAC.49.7.3050-3052.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  4 in total

1.  Interaction of plasmid and host quinolone resistance.

Authors:  Luis Martínez-Martínez; Alvaro Pascual; Isabel García; John Tran; George A Jacoby
Journal:  J Antimicrob Chemother       Date:  2003-02-25       Impact factor: 5.790

2.  Interaction of the plasmid-encoded quinolone resistance protein Qnr with Escherichia coli DNA gyrase.

Authors:  John H Tran; George A Jacoby; David C Hooper
Journal:  Antimicrob Agents Chemother       Date:  2005-01       Impact factor: 5.191

3.  Mechanism of plasmid-mediated quinolone resistance.

Authors:  John H Tran; George A Jacoby
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-09       Impact factor: 11.205

4.  Escherichia coli topoisomerase IV. Purification, characterization, subunit structure, and subunit interactions.

Authors:  H Peng; K J Marians
Journal:  J Biol Chem       Date:  1993-11-15       Impact factor: 5.157

  4 in total
  63 in total

1.  Quinolone induction of qnrVS1 in Vibrio splendidus and plasmid-carried qnrS1 in Escherichia coli, a mechanism independent of the SOS system.

Authors:  Ryo Okumura; Chun-Hsing Liao; Mariah Gavin; George A Jacoby; David C Hooper
Journal:  Antimicrob Agents Chemother       Date:  2011-09-19       Impact factor: 5.191

2.  Structural and biochemical analysis of the pentapeptide repeat protein EfsQnr, a potent DNA gyrase inhibitor.

Authors:  Subray S Hegde; Matthew W Vetting; Lesley A Mitchenall; Anthony Maxwell; John S Blanchard
Journal:  Antimicrob Agents Chemother       Date:  2010-10-11       Impact factor: 5.191

3.  Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid.

Authors:  Georgina Cox; Gary S Thompson; Huw T Jenkins; Frank Peske; Andreas Savelsbergh; Marina V Rodnina; Wolfgang Wintermeyer; Steve W Homans; Thomas A Edwards; Alexander J O'Neill
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-20       Impact factor: 11.205

4.  Mobilizable IncQ-related plasmid carrying a new quinolone resistance gene, qnrS2, isolated from the bacterial community of a wastewater treatment plant.

Authors:  Gabriele Bönemann; Michael Stiens; Alfred Pühler; Andreas Schlüter
Journal:  Antimicrob Agents Chemother       Date:  2006-09       Impact factor: 5.191

5.  Pentapeptide repeat proteins.

Authors:  Matthew W Vetting; Subray S Hegde; J Eduardo Fajardo; Andras Fiser; Steven L Roderick; Howard E Takiff; John S Blanchard
Journal:  Biochemistry       Date:  2006-01-10       Impact factor: 3.162

6.  In vivo selection of fluoroquinolone-resistant Escherichia coli isolates expressing plasmid-mediated quinolone resistance and expanded-spectrum beta-lactamase.

Authors:  Laurent Poirel; Johann D D Pitout; Lucy Calvo; Jose-Manuel Rodriguez-Martinez; Deirdre Church; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2006-04       Impact factor: 5.191

7.  qnr prevalence in ceftazidime-resistant Enterobacteriaceae isolates from the United States.

Authors:  A Robicsek; J Strahilevitz; D F Sahm; G A Jacoby; D C Hooper
Journal:  Antimicrob Agents Chemother       Date:  2006-08       Impact factor: 5.191

8.  Prevalence and genetic analysis of plasmid-mediated quinolone resistance determinants QnrA and QnrS in Enterobacteriaceae isolates from a French university hospital.

Authors:  Laurent Poirel; Cécile Leviandier; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2006-09-18       Impact factor: 5.191

9.  Characterization of small ColE-like plasmids mediating widespread dissemination of the qnrB19 gene in commensal enterobacteria.

Authors:  Lucia Pallecchi; Eleonora Riccobono; Samanta Sennati; Antonia Mantella; Filippo Bartalesi; Christian Trigoso; Eduardo Gotuzzo; Alessandro Bartoloni; Gian Maria Rossolini
Journal:  Antimicrob Agents Chemother       Date:  2009-12-14       Impact factor: 5.191

10.  Characterization of two potentially universal turn motifs that shape the repeated five-residues fold--crystal structure of a lumenal pentapeptide repeat protein from Cyanothece 51142.

Authors:  Garry W Buchko; Shuisong Ni; Howard Robinson; Eric A Welsh; Himadri B Pakrasi; Michael A Kennedy
Journal:  Protein Sci       Date:  2006-11       Impact factor: 6.725

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