| Literature DB >> 15980392 |
Joan Gavaldà1, María-Teresa Martín, Pedro López, Xavier Gomis, José-Luís Ramírez, Dolors Rodríguez, Oscar Len, Yolanda Puigfel, Isabel Ruíz, Albert Pahissa.
Abstract
The efficacy of therapeutic aerosolized amphotericin B (AMB) was studied in a steroid-immunosuppressed murine model of invasive pulmonary aspergillosis. Nebulized liposomal AMB can be a valid approach to the treatment of this infection, with subjects showing significantly improved survival relative to that of subjects given intravenous deoxycholate AMB, as well as lower lung weights and pulmonary glucosamine levels.Entities:
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Year: 2005 PMID: 15980392 PMCID: PMC1168712 DOI: 10.1128/AAC.49.7.3028-3030.2005
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191