Literature DB >> 15980269

Simvastatin given for 3 days can inhibit thrombin generation and activation of factor V and enhance factor Va inactivation in hypercholesterolemic patients.

Anetta Undas, Magdalena Celinska-Löwenhoff, Kathleen E Brummel-Ziedins, Jan Brozek, Andrew Szczeklik, Kenneth G Mann.   

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Year:  2005        PMID： 15980269      PMCID： PMC1298245          DOI： 10.1161/01.ATV.0000168913.25278.38

Source DB:  PubMed          Journal:  Arterioscler Thromb Vasc Biol        ISSN： 1079-5642            Impact factor:   8.311


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  4 in total

1.  Blood coagulation at the site of microvascular injury: effects of low-dose aspirin.

Authors:  A Undas; K Brummel; J Musial; K G Mann; A Szczeklik
Journal:  Blood       Date:  2001-10-15       Impact factor: 22.113

Review 2.  Statins and blood coagulation.

Authors:  Anetta Undas; Kathleen E Brummel-Ziedins; Kenneth G Mann
Journal:  Arterioscler Thromb Vasc Biol       Date:  2004-11-29       Impact factor: 8.311

3.  Simvastatin depresses blood clotting by inhibiting activation of prothrombin, factor V, and factor XIII and by enhancing factor Va inactivation.

Authors:  A Undas; K E Brummel; J Musial; K G Mann; A Szczeklik
Journal:  Circulation       Date:  2001-05-08       Impact factor: 29.690

4.  Pitavastatin-induced thrombomodulin expression by endothelial cells acts via inhibition of small G proteins of the Rho family.

Authors:  Katsuhiko Masamura; Koji Oida; Hideo Kanehara; Jinya Suzuki; Shuichi Horie; Hidemi Ishii; Isamu Miyamori
Journal:  Arterioscler Thromb Vasc Biol       Date:  2003-02-06       Impact factor: 8.311
  4 in total
  14 in total

1.  Off-target properties of pharmacotherapy and the importance of mechanistic investigations in early clinical phase drug development.

Authors:  Richard C Becker
Journal:  J Thromb Thrombolysis       Date:  2007-02-03       Impact factor: 2.300

2.  Influence of statin therapy at time of stroke onset on functional outcome among patients with atrial fibrillation.

Authors:  Darae Ko; Jonathan L Thigpen; James A Otis; Kristen Forster; Lori Henault; Emily Quinn; Yorghos Tripodis; Peter B Berger; Nita Limdi; Elaine M Hylek
Journal:  Int J Cardiol       Date:  2016-10-24       Impact factor: 4.164

3.  Statin effect on thrombin inhibitor effectiveness during percutaneous coronary intervention: a post-hoc analysis from the ISAR-REACT 3 trial.

Authors:  Ahmed A Khattab; Gjin Ndrepepa; Stefanie Schulz; Franz-Josef Neumann; Julinda Mehilli; Heinz Joachim Büttner; Jürgen Pache; Melchior Seyfarth; Josef Dirschinger; Adnan Kastrati; Peter B Berger; Albert Schömig; Gert Richardt
Journal:  Clin Res Cardiol       Date:  2011-02-11       Impact factor: 5.460

4.  Atorvastatin Reduces In Vivo Fibrin Deposition and Macrophage Accumulation, and Improves Primary Patency Duration and Maturation of Murine Arteriovenous Fistula.

Authors:  Jie Cui; Chase W Kessinger; Harkamal S Jhajj; Madeleine S Grau; Sanjay Misra; Peter Libby; Jason R McCarthy; Farouc A Jaffer
Journal:  J Am Soc Nephrol       Date:  2020-03-09       Impact factor: 10.121

5.  Systemic blood coagulation activation in acute coronary syndromes.

Authors:  Anetta Undas; Konstanty Szułdrzyński; Kathleen E Brummel-Ziedins; Wiesława Tracz; Krzysztof Zmudka; Kenneth G Mann
Journal:  Blood       Date:  2008-10-17       Impact factor: 22.113

6.  Statins but not aspirin reduce thrombotic risk assessed by thrombin generation in diabetic patients without cardiovascular events: the RATIONAL trial.

Authors:  Alejandro Macchia; Nicolás Laffaye; Pablo D Comignani; Elena Cornejo Pucci; Cecilia Igarzabal; Alejandra S Scazziota; Lourdes Herrera; Javier A Mariani; Julio C Bragagnolo; Hugo Catalano; Gianni Tognoni; Antonio Nicolucci
Journal:  PLoS One       Date:  2012-03-28       Impact factor: 3.240

7.  Effects of simvastatin on tissue factor pathway of blood coagulation in STATCOPE (Simvastatin in the prevention of COPD exacerbations) trial.

Authors:  A Koneti Rao; Fabiola Del Carpio-Cano; Sumalaxmi Janapati; Huaqing Zhao; Helen Voelker; Xiaoning Lu; Gerard Criner
Journal:  J Thromb Haemost       Date:  2021-04-12       Impact factor: 16.036

8.  Statin treatment and risk of recurrent venous thromboembolism: a nationwide cohort study.

Authors:  Cu Dinh Nguyen; Charlotte Andersson; Thomas Bo Jensen; Anne Gjesing; Anne-Marie Schjerning Olsen; Carolina Malta Hansen; Harry Büller; Christian Torp-Pedersen; Gunnar H Gislason
Journal:  BMJ Open       Date:  2013-11-07       Impact factor: 2.692

9.  Increased Clot Formation in the Absence of Increased Thrombin Generation in Patients with Peripheral Arterial Disease: A Case-Control Study.

Authors:  Marie-Claire F Kleinegris; Joke Konings; Jan W Daemen; Yvonne Henskens; Bas de Laat; Henri M H Spronk; Arina J Ten Cate-Hoek; Hugo Ten Cate
Journal:  Front Cardiovasc Med       Date:  2017-04-20

Review 10.  Anticoagulants and Statins As Pharmacological Agents in Free Flap Surgery: Current Rationale.

Authors:  Adnan Pršić; Elizabeth Kiwanuka; Stephanie A Caterson; Edward J Caterson
Journal:  Eplasty       Date:  2015-11-20
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