Literature DB >> 15975315

Regulative effect of traditional Chinese medicine on gene-expression related to precancerous lesion of gastric cancer.

Fang-shi Zhu1, Jian-min Si.   

Abstract

The gene-expression changes related with precancerous lesion of gastric cancer (PLGC) are surveyed. Not only the regulative effect of traditional Chinese medicine (TCM) on oncogene, antioncogene and anti-apoptosis gene that are related with PLGC is analyzed, but also current research state is presented. It's showed that TCM has effects of therapy and inversion on PLGC. These effects are related with the inhibition to related oncogene expression, the regulation and activation to the deletion of antioncogene, the inhibition to the high-expression of mutant gene-protein about antioncogene, and the regulative function to anti-apoptosis gene.

Entities:  

Mesh：

Year:  2005        PMID： 15975315     DOI： 10.1007/BF02835759

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN： 1672-0415            Impact factor:   1.978


  7 in total

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Authors:  J D Hunt; R Mera; A Strimas; A T Gillespie; B Ruiz; P Correa; E T Fontham
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Journal:  Cancer Res       Date:  1997-06-01       Impact factor: 12.701

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Journal:  Cancer       Date:  1993-09-15       Impact factor: 6.860

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Authors:  J F Kerr; C M Winterford; B V Harmon
Journal:  Cancer       Date:  1994-04-15       Impact factor: 6.860

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Authors:  P Zhou; W Jiang; C M Weghorst; I B Weinstein
Journal:  Cancer Res       Date:  1996-01-01       Impact factor: 12.701

7.  [Relationship between Helicobacter pylori infection and expressions of tumor suppressor genes in gastric carcinoma and related lesions].

Authors:  Su-fang Tian; Yong-yan Xiong; Shao-ping Yu; Jing Lan
Journal:  Ai Zheng       Date:  2002-09
  7 in total

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