Literature DB >> 15968945

Three-dimensional numeric simulation of flow through an aortic bileaflet valve in a realistic model of aortic root.

Mauro Grigioni1, Carla Daniele, Costantino Del Gaudio, Umberto Morbiducci, Antonio Balducci, Giuseppe D'Avenio, Vincenzo Barbaro.   

Abstract

A three-dimensional, realistic model of an aortic mechanical heart valve and Valsalva sinuses was developed to predict, by means of a numerical time dependent simulation, the flow field during a fraction of the systolic period. The numeric simulation was performed upon a model of valve similar to a Carbomedics 27 mm placed in a physiologic aortic root shaped model, in which no symmetry planes were exploited to reach a more realistic level. Input data for the simulation have been acquired during an experimental session on the same valve, according to the guidelines of testing protocol for prosthetic heart valves. Flow was assumed to be Newtonian and laminar at low regime and the leaflets fixed in the fully open position. The forward flow of the systolic phase was investigated, and a comparison with experimental results was performed at peak systole, the most representative point of the cardiac cycle. The results of this simulation furnished a reasonable indication (in terms of fluid dynamics) parameters downstream of the prosthetic device, especially in Valsalva sinuses, the role of which is proven to affect the valve's performance.

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Year:  2005        PMID: 15968945     DOI: 10.1097/01.mat.0000159384.36271.2c

Source DB:  PubMed          Journal:  ASAIO J        ISSN: 1058-2916            Impact factor:   2.872


  7 in total

1.  The effect of implantation orientation of a bileaflet mechanical heart valve on kinematics and hemodynamics in an anatomic aorta.

Authors:  Iman Borazjani; Fotis Sotiropoulos
Journal:  J Biomech Eng       Date:  2010-11       Impact factor: 2.097

Review 2.  Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting.

Authors:  Mohamad Shukri Zakaria; Farzad Ismail; Masaaki Tamagawa; Ahmad Fazli Abdul Aziz; Surjatin Wiriadidjaja; Adi Azrif Basri; Kamarul Arifin Ahmad
Journal:  Med Biol Eng Comput       Date:  2017-07-26       Impact factor: 2.602

3.  Device Thrombogenicity Emulator (DTE)--design optimization methodology for cardiovascular devices: a study in two bileaflet MHV designs.

Authors:  Michalis Xenos; Gaurav Girdhar; Yared Alemu; Jolyon Jesty; Marvin Slepian; Shmuel Einav; Danny Bluestein
Journal:  J Biomech       Date:  2010-05-21       Impact factor: 2.712

4.  A parallel overset-curvilinear-immersed boundary framework for simulating complex 3D incompressible flows.

Authors:  Iman Borazjani; Liang Ge; Trung Le; Fotis Sotiropoulos
Journal:  Comput Fluids       Date:  2013-04-01       Impact factor: 3.013

5.  High-resolution fluid-structure interaction simulations of flow through a bi-leaflet mechanical heart valve in an anatomic aorta.

Authors:  Iman Borazjani; Liang Ge; Fotis Sotiropoulos
Journal:  Ann Biomed Eng       Date:  2009-10-06       Impact factor: 3.934

6.  Does transcatheter aortic valve alignment matter?

Authors:  Jacob Andrew Salmonsmith; Andrea Ducci; Gaetano Burriesci
Journal:  Open Heart       Date:  2019-11-21

7.  Physiological vortices in the sinuses of Valsalva: An in vitro approach for bio-prosthetic valves.

Authors:  Riccardo Toninato; Jacob Salmon; Francesca Maria Susin; Andrea Ducci; Gaetano Burriesci
Journal:  J Biomech       Date:  2016-06-01       Impact factor: 2.712

  7 in total

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