Literature DB >> 15965793

Medication for older people--aspects of rational therapy from the general practitioner's point of view.

M Vass1, C Hendriksen.   

Abstract

This paper discusses GP perspectives on the principles underlying rational pharmacotherapy for older people. The rising use of prescription medicine forces the GP to balance the benefit of evidence group-based appropriate drug use against the problems arising when medication is given to older people and to consider different approaches when evaluating evidence of risk and benefit for the individual. Old people are facing a considerable risk of adverse drug reactions and recent initiatives, including the Continuous Medical Educational Efforts Programme, address issues of inappropriate prescribing practices. The authors recommend and present tools enabling the GP to focus on 'the core prescribing situation'. The logistics to optimise medication including compliance, the use of modern IT and better collaboration and communication between primary and secondary care are discussed. The authors state that a number of pharmacological regimens for older people are outperformed by non-pharmacological treatment alternatives involving competent individualised counselling and public provision of easy (transportation) possibilities for joining centres offering staff and equipment for physical and social activity (including basal aids for hearing and sight).

Entities:  

Mesh:

Year:  2005        PMID: 15965793     DOI: 10.1007/s00391-005-0310-1

Source DB:  PubMed          Journal:  Z Gerontol Geriatr        ISSN: 0948-6704            Impact factor:   1.281


  8 in total

1.  Impact of inappropriate drug use on mortality and functional status in representative community dwelling elders.

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2.  Evidence based medicine, guidelines and common sense.

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Authors:  Lars Bjerrum; Morten Andersen; Gert Petersen; Jakob Kragstrup
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4.  Feasible model for prevention of functional decline in older people: municipality-randomized, controlled trial.

Authors:  Mikkel Vass; Kirsten Avlund; Jørgen Lauridsen; Carsten Hendriksen
Journal:  J Am Geriatr Soc       Date:  2005-04       Impact factor: 5.562

5.  Tiredness as determinant of subsequent use of health and social services among nondisabled elderly people.

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6.  Suboptimal prescribing in elderly outpatients: potentially harmful drug-drug and drug-disease combinations.

Authors:  Chunliu Zhan; Rosaly Correa-de-Araujo; Arlene S Bierman; Judy Sangl; Marlene R Miller; Stephen W Wickizer; Daniel Stryer
Journal:  J Am Geriatr Soc       Date:  2005-02       Impact factor: 5.562

Review 7.  Antiplatelet agents and anticoagulants for hypertension.

Authors:  G Y H Lip; D C Felmeden
Journal:  Cochrane Database Syst Rev       Date:  2004

8.  Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients.

Authors:  Munir Pirmohamed; Sally James; Shaun Meakin; Chris Green; Andrew K Scott; Thomas J Walley; Keith Farrar; B Kevin Park; Alasdair M Breckenridge
Journal:  BMJ       Date:  2004-07-03
  8 in total
  3 in total

Review 1.  [Delirium in the elderly].

Authors:  Manfred Gogol
Journal:  Z Gerontol Geriatr       Date:  2008-10-30       Impact factor: 1.281

2.  Physiologically Based Pharmacokinetic Modelling to Identify Pharmacokinetic Parameters Driving Drug Exposure Changes in the Elderly.

Authors:  Felix Stader; Hannah Kinvig; Melissa A Penny; Manuel Battegay; Marco Siccardi; Catia Marzolini
Journal:  Clin Pharmacokinet       Date:  2020-03       Impact factor: 6.447

3.  Tools in polypharmacy. Current evidence from observational and controlled studies.

Authors:  P Dovjak
Journal:  Z Gerontol Geriatr       Date:  2012-08       Impact factor: 1.281

  3 in total

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