Literature DB >> 15954529

Generation of landomycin D-producing strain Streptomyces globisporus LD3.

B Ostash1, I Kozarevska, V Fedorenko.   

Abstract

Rhodinosyl transferase gene lndGT4, governing the conversion of the disaccharide oligoketide ('polyketide') landomycin D into a trisaccharide derivative landomycin E, was deleted in Streptomyces globisporus 1912 genome. Possible resistance mechanisms that protect the resulting landomycin D-producing mutant strain S. globisporus LD3 against the toxic action of landomycins were determined.

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Year:  2005        PMID： 15954529     DOI： 10.1007/BF02931289

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.629


  11 in total

1.  Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.

Authors:  M J Lozano; L L Remsing; L M Quirós; A F Braña; E Fernández; C Sánchez; C Méndez; J Rohr; J A Salas
Journal:  J Biol Chem       Date:  2000-02-04       Impact factor: 5.157

2.  The Streptomyces peucetius dpsY and dnrX genes govern early and late steps of daunorubicin and doxorubicin biosynthesis.

Authors:  N Lomovskaya; Y Doi-Katayama; S Filippini; C Nastro; L Fonstein; M Gallo; A L Colombo; C R Hutchinson
Journal:  J Bacteriol       Date:  1998-05       Impact factor: 3.490

3.  Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.

Authors:  M Bierman; R Logan; K O'Brien; E T Seno; R N Rao; B E Schoner
Journal:  Gene       Date:  1992-07-01       Impact factor: 3.688

4.  [Interspecies conjugation of Escherichia coli-Streptomyces globisporus 1912 using integrative plasmid pSET152 and its derivatives].

Authors:  A N Luzhetskiĭ; B E Ostash; V A Fedorenko
Journal:  Genetika       Date:  2001-10

5.  Landomycins, new angucycline antibiotics from Streptomyces sp. I. Structural studies on landomycins A-D.

Authors:  T Henkel; J Rohr; J M Beale; L Schwenen
Journal:  J Antibiot (Tokyo)       Date:  1990-05       Impact factor: 2.649

6.  [The sensitivity to landomycins A and E of streptomycetes, producers of polyketide antibiotics].

Authors:  B P Matseliukh; T A Konovalova; L V Polishchuk; O I Bambura
Journal:  Mikrobiol Z       Date:  1998 Jan-Feb

7.  Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus.

Authors:  L M Quirós; I Aguirrezabalaga; C Olano; C Méndez; J A Salas
Journal:  Mol Microbiol       Date:  1998-06       Impact factor: 3.501

8.  Engineering deoxysugar biosynthetic pathways from antibiotic-producing microorganisms. A tool to produce novel glycosylated bioactive compounds.

Authors:  Leticia Rodríguez; Ignacio Aguirrezabalaga; Nerea Allende; Alfredo F Braña; Carmen Méndez; José A Salas
Journal:  Chem Biol       Date:  2002-06

9.  Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus.

Authors:  Bohdan Ostash; Uwe Rix; Lily L Remsing Rix; Tao Liu; Felipe Lombo; Andriy Luzhetskyy; Oleksandr Gromyko; Chenchen Wang; Alfredo F Braña; Carmen Méndez; José A Salas; Victor Fedorenko; Jürgen Rohr
Journal:  Chem Biol       Date:  2004-04

10.  Targeted disruption of Streptomyces globisporus lndF and lndL cyclase genes involved in landomycin E biosynthesis.

Authors:  B Ostash; Y Rebets; V Yuskevich; A Luzhetskyy; V Tkachenko; V Fedorenko
Journal:  Folia Microbiol (Praha)       Date:  2003       Impact factor: 2.629
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  1 in total

1.  Relationship between volatile odorous substances and production of avermectins by Streptomyces avermitilis.

Authors:  T Rezanka; M Sobotka; A Prell; K Sigler
Journal:  Folia Microbiol (Praha)       Date:  2007       Impact factor: 2.629
  1 in total

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