Literature DB >> 15953639

Botulinum toxin for palliative treatment of epiphora in a patient with canalicular obstruction.

Alexander H Tu1, Eli L Chang.   

Abstract

OBJECTIVE: To describe the use of botulinum toxin injection of the lacrimal gland for palliative treatment of epiphora secondary to canalicular obstruction from docetaxel therapy.
DESIGN: Case report. INTERVENTION: A 50-year-old female with bilateral canalicular obstruction secondary to docetaxel therapy received botulinum toxin injections (5 units each) into the lacrimal glands of both eyes.
RESULTS: Symptomatic epiphora of the affected eyes was reduced after 2 weeks. No side effects were observed.
CONCLUSIONS: Botulinum toxin injection of the lacrimal gland is an effective palliative treatment for epiphora secondary to canalicular obstruction from docetaxel therapy.

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Year:  2005        PMID: 15953639     DOI: 10.1016/j.ophtha.2005.02.022

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  7 in total

1.  Repeated injections of botulinum toxin-A for epiphora in lacrimal drainage disorders: qualitative and quantitative assessment.

Authors:  Chanjoo Ahn; Sunah Kang; Ho-Seok Sa
Journal:  Eye (Lond)       Date:  2019-02-14       Impact factor: 3.775

2.  Comparison of botulinum toxin-A injection in lacrimal gland and conjunctivodacryocystorhinostomy for treatment of epiphora due to proximal lacrimal system obstruction.

Authors:  P Kaynak; G O Karabulut; C Ozturker; K Fazil; Y O Arat; I Perente; S Akar; O F Yilmaz; A Demirok
Journal:  Eye (Lond)       Date:  2016-05-20       Impact factor: 3.775

Review 3.  A review on use of botulinum toxin for intractable lacrimal drainage disorders.

Authors:  Swati Singh; Mohammad Javed Ali; Friedrich Paulsen
Journal:  Int Ophthalmol       Date:  2017-08-01       Impact factor: 2.031

4.  Current practice trends for lacrimal gland neurotoxin in the management of epiphora-a BOPSS survey.

Authors:  Micheal A O'Rourke; Paul S Cannon
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2021-10-18       Impact factor: 3.117

5.  Intraglandular injection of botulinum toxin a reduces tear production in rabbits.

Authors:  Anna M Demetriades; Ilya M Leyngold; Sam D'Anna; Allen O Eghrari; Dave G Emmert; Michael P Grant; Shannath L Merbs
Journal:  Ophthalmic Plast Reconstr Surg       Date:  2013 Jan-Feb       Impact factor: 1.746

Review 6.  A Review of Periocular Botulinum Neurotoxin on the Tear Film Homeostasis and the Ocular Surface Change.

Authors:  Ren-Wen Ho; Po-Chiung Fang; Cheng-Hsien Chang; Yu-Peng Liu; Ming-Tse Kuo
Journal:  Toxins (Basel)       Date:  2019-01-24       Impact factor: 4.546

7.  Outcomes of lacrimal gland injection of botulinum toxin in functional versus nonfunctional epiphora.

Authors:  Swati Singh; Akshay Gopinathan Nair; Md Shahid Alam; Bipasha Mukherjee
Journal:  Oman J Ophthalmol       Date:  2019 May-Aug
  7 in total

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