PURPOSE: To report the electrophysiologic findings in a patient with lipaemia retinalis. DESIGN: Observational case report. METHODS: An 11-year-old girl with diabetes had hyperlipidemia and presented for ophthalmologic consultation. Fundus examinations revealed milky discoloration of retinal vessels in both eyes. Laboratory testing disclosed hyperglycemia and markedly elevated level of triglycerides and cholesterol. Although the visual acuity was not affected, the electroretinograms showed decrease amplitudes of a- and b-wave in both cone and rod responses. RESULTS: After correction of blood sugar and lipids with insulin and diet control, the lipaemia retinalis resolved, and the impaired ERG response reversed within 1 week. CONCLUSIONS: Lipaemia retinalis usually resolves rapidly without visual impairment after correction of hyperlipidemia. The reversible deficits of electroretinogram response in lipaemia retinalis are reported for the first time. High level of triglycerides or cholesterol or both may impair retinal function. The mechanism of an impaired electroretinogram remained speculative.
PURPOSE: To report the electrophysiologic findings in a patient with lipaemia retinalis. DESIGN: Observational case report. METHODS: An 11-year-old girl with diabetes had hyperlipidemia and presented for ophthalmologic consultation. Fundus examinations revealed milky discoloration of retinal vessels in both eyes. Laboratory testing disclosed hyperglycemia and markedly elevated level of triglycerides and cholesterol. Although the visual acuity was not affected, the electroretinograms showed decrease amplitudes of a- and b-wave in both cone and rod responses. RESULTS: After correction of blood sugar and lipids with insulin and diet control, the lipaemia retinalis resolved, and the impaired ERG response reversed within 1 week. CONCLUSIONS: Lipaemia retinalis usually resolves rapidly without visual impairment after correction of hyperlipidemia. The reversible deficits of electroretinogram response in lipaemia retinalis are reported for the first time. High level of triglycerides or cholesterol or both may impair retinal function. The mechanism of an impaired electroretinogram remained speculative.
Authors: Cara E Capitena; Holly J Wagoner; Christopher M Ruzas; Tellen D Bennett; Peter R Baker; Jennifer L Jung; James D Weisfeld-Adams Journal: J Inherit Metab Dis Date: 2016-08-12 Impact factor: 4.982
Authors: Waleed K Alsarhani; Fadwa F Al Adel; Abdullah Alamri; Rahaf M Al Malawi; Abdulrahman F AlBloushi Journal: BMC Ophthalmol Date: 2022-07-06 Impact factor: 2.086
Authors: Nehal M El-Koofy; Yasmeen A Abdo; Dina El-Fayoumi; Amanne F Esmael; Mohamed A Elmonem; Zahraa Ezzeldin Journal: Lipids Health Dis Date: 2021-04-20 Impact factor: 3.876
Authors: Jon Ortiz de Salido-Menchaca; Manuel Antonio Tazón-Varela; David de la Hera-Vegas; Rosa Herreras-Martínez; Sergio Andrés Álvarez-Agudelo; Nuria Arencibia-Hernández Journal: Colomb Med (Cali) Date: 2021-03-30