Real-time 3D echocardiography-guided transcatheter device closure of atrial septal defects.

We report our initial experience using real-time (live) three-dimensional (3D) transthoracic echocardiographic imaging under conscious sedation as a guide for transcatheter device closure of atrial septal defects. We believe this may be a feasible, safe, and effective alternative to the standard practice of transesophageal echocardiography, which requires general anesthesia and endotacheal intubation. Three-dimensional echocardiography may better define atrial septal anatomy and adjacent structures in planning for and performing percutaneous device closure of selected atrial septal defects.