Literature DB >> 15950468

Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents.

Vishnu K Tandon1, Dharmendra B Yadav, Ravindra V Singh, Meenu Vaish, Ashok K Chaturvedi, Praveen K Shukla.   

Abstract

A series of 1,4-naphthoquinone derivatives were synthesized and evaluated for antibacterial and antiviral activities. The structure-activity relationships of these compounds were also studied. The results suggest that compounds 9-22 showed in vitro marked antibacterial activity. Compounds 4c and 7a showed inhibitory effect against RNA dependent RNA polymerase induced poliovirus type 2 infected HeLa cells.

Entities:  

Mesh:

Substances:

Year:  2005        PMID: 15950468     DOI: 10.1016/j.bmcl.2005.04.075

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  11 in total

1.  High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv.

Authors:  Subramaniam Ananthan; Ellen R Faaleolea; Robert C Goldman; Judith V Hobrath; Cecil D Kwong; Barbara E Laughon; Joseph A Maddry; Alka Mehta; Lynn Rasmussen; Robert C Reynolds; John A Secrist; Nice Shindo; Dustin N Showe; Melinda I Sosa; William J Suling; E Lucile White
Journal:  Tuberculosis (Edinb)       Date:  2009-09-15       Impact factor: 3.131

2.  Suppressing VEGF-A/VEGFR-2 Signaling Contributes to the Anti-Angiogenic Effects of PPE8, a Novel Naphthoquinone-Based Compound.

Authors:  Ming-Jen Hsu; Han-Kun Chen; Jin-Cherng Lien; Yu-Han Huang; Shiu-Wen Huang
Journal:  Cells       Date:  2022-07-05       Impact factor: 7.666

3.  Synthesis, Structural, DNA Binding and Cleavage Studies of Cu(II) Complexes Containing Benzothiazole Cored Schiff Bases.

Authors:  Somapangu Tejaswi; Marri Pradeep Kumar; Aveli Rambabu; Narendrula Vamsikrishna
Journal:  J Fluoresc       Date:  2016-08-27       Impact factor: 2.217

4.  Synthesis of Schiff bases of naphtha[1,2-d]thiazol-2-amine and metal complexes of 2-(2'-hydroxy)benzylideneaminonaphthothiazole as potential antimicrobial agents.

Authors:  Faizul Azam; Satendra Singh; Sukhbir Lal Khokhra; Om Prakash
Journal:  J Zhejiang Univ Sci B       Date:  2007-06       Impact factor: 3.066

5.  Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases.

Authors:  Shugeng Cao; Brian T Murphy; Caleb Foster; John S Lazo; David G I Kingston
Journal:  Bioorg Med Chem       Date:  2008-11-08       Impact factor: 3.641

6.  Synthesis and antimicrobial activity of N-substituted-β-amino acid derivatives containing 2-hydroxyphenyl, benzo[b]phenoxazine and quinoxaline moieties.

Authors:  Kristina Mickevičienė; Rūta Baranauskaitė; Kristina Kantminienė; Maryna Stasevych; Olena Komarovska-Porokhnyavets; Volodymyr Novikov
Journal:  Molecules       Date:  2015-02-13       Impact factor: 4.411

7.  A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections.

Authors:  Javier Campanini-Salinas; Juan Andrades-Lagos; Gerardo Gonzalez Rocha; Duane Choquesillo-Lazarte; Soledad Bollo Dragnic; Mario Faúndez; Pedro Alarcón; Francisco Silva; Roberto Vidal; Edison Salas-Huenuleo; Marcelo Kogan; Jaime Mella; Gonzalo Recabarren Gajardo; David Vásquez-Velásquez
Journal:  Molecules       Date:  2018-07-19       Impact factor: 4.411

8.  Oxidative radical coupling of hydroquinones and thiols using chromic acid: one-pot synthesis of quinonyl alkyl/aryl thioethers.

Authors:  T P Adarsh Krishna; Sakthivel Pandaram; Suresh Chinnasamy; Andivelu Ilangovan
Journal:  RSC Adv       Date:  2020-05-21       Impact factor: 4.036

9.  Antimicrobial, antioxidant, toxicity and phytochemical assessment of extracts from Acmella uliginosa, a leafy-vegetable consumed in Bénin, West Africa.

Authors:  Latifou Lagnika; Abdou Madjid O Amoussa; Rafatou A A Adjileye; Anatole Laleye; Ambaliou Sanni
Journal:  BMC Complement Altern Med       Date:  2016-01-27       Impact factor: 3.659

10.  New Pyrimidinone-Fused 1,4-Naphthoquinone Derivatives Inhibit the Growth of Drug Resistant Oral Bacteria.

Authors:  Kyungmin Kim; Daseul Kim; Hyunjin Lee; Tae Hoon Lee; Ki-Young Kim; Hakwon Kim
Journal:  Biomedicines       Date:  2020-06-15
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.