Literature DB >> 15948677

The promise of cytokine antibody arrays in the drug discovery process.

Ruo-Pan Huang1, Weimin Yang, Dongzi Yang, Lisa Flowers, Ira R Horowitz, Xuan Cao, Ruochun Huang.   

Abstract

The introduction of cytokine antibody arrays has added a new approach for investigators to simultaneously measure multiple cytokine levels in biological samples. Several different platforms have been developed. The ability to measure hundreds of cytokine levels with high specificity and sensitivity within a very limited amount of samples is a powerful tool. Many investigators worldwide have applied this novel technology in their biomedical research, particularly in drug discovery. Undoubtedly, the technology will continue to be improved and the application increased in the next several years.

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Year:  2005        PMID: 15948677     DOI: 10.1517/14728222.9.3.601

Source DB:  PubMed          Journal:  Expert Opin Ther Targets        ISSN: 1472-8222            Impact factor:   6.902


  7 in total

Review 1.  Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer.

Authors:  James F Rusling; Challa V Kumar; J Silvio Gutkind; Vyomesh Patel
Journal:  Analyst       Date:  2010-07-08       Impact factor: 4.616

2.  Comparison of hydroxylated print additives on antibody microarray performance.

Authors:  Peng Wu; David W Grainger
Journal:  J Proteome Res       Date:  2006-11       Impact factor: 4.466

3.  Protein subcellular localization profiling of breast cancer cells by dissociable antibody microarray staining.

Authors:  Guanyuan Fu; X Cynthia Song; Xufen Yang; Tao Peng; Yingjian Wang; G Wayne Zhou
Journal:  Proteomics       Date:  2010-04       Impact factor: 3.984

4.  Identification of predictive circulating biomarkers of bevacizumab-containing regimen efficacy in pre-treated metastatic colorectal cancer patients.

Authors:  A Abajo; V Boni; I Lopez; M Gonzalez-Huarriz; N Bitarte; J Rodriguez; R Zarate; E Bandres; J Garcia-Foncillas
Journal:  Br J Cancer       Date:  2012-06-14       Impact factor: 7.640

Review 5.  New Insights into the Tumor Microenvironment Utilizing Protein Array Technology.

Authors:  Wei Huang; Shuhong Luo; Rob Burgess; Yu-Hua Yi; Gordon F Huang; Ruo-Pan Huang
Journal:  Int J Mol Sci       Date:  2018-02-13       Impact factor: 5.923

6.  Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.

Authors:  Mathieu Darsigny; Jean-Philippe Babeu; Andrée-Anne Dupuis; Emma E Furth; Ernest G Seidman; Emile Lévy; Elena F Verdu; Fernand-Pierre Gendron; François Boudreau
Journal:  PLoS One       Date:  2009-10-29       Impact factor: 3.240

Review 7.  3D-Printed Immunosensor Arrays for Cancer Diagnostics.

Authors:  Mohamed Sharafeldin; Karteek Kadimisetty; Ketki S Bhalerao; Tianqi Chen; James F Rusling
Journal:  Sensors (Basel)       Date:  2020-08-12       Impact factor: 3.576

  7 in total

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