Literature DB >> 15947177

Uterine fibroids: the elephant in the room.

Cheryl Lyn Walker1, Elizabeth A Stewart.   

Abstract

Uterine fibroids (leiomyomas) have historically been viewed as important chiefly as the major indication for hysterectomy. As new therapies are developed, the heterogeneity of this disease becomes therapeutically relevant. An awareness of the role of genetics, the extracellular matrix, and hormones in tumor etiology is key to understanding this disease.

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Year:  2005        PMID: 15947177     DOI: 10.1126/science.1112063

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  180 in total

1.  Analysis of molecular cytogenetic alterations in uterine leiomyosarcoma by array-based comparative genomic hybridization.

Authors:  Mohammad Raish; Mohsin Khurshid; Mushtaq Ahmad Ansari; Pankaj Kumar Chaturvedi; Su-Mi Bae; Jang Heub Kim; Eun Kyung Park; Dong Chun Park; Woong Shick Ahn
Journal:  J Cancer Res Clin Oncol       Date:  2012-03-15       Impact factor: 4.553

2.  Different characteristics of mitochondrial microsatellite instability between uterine leiomyomas and leiomyosarcomas.

Authors:  Jae-Ho Lee; Tae-Yung Ryu; Chi-Heum Cho; Dae-Kwang Kim
Journal:  Pathol Oncol Res       Date:  2010-09-18       Impact factor: 3.201

3.  An endocrine-disrupting chemical, fenvalerate, induces cell cycle progression and collagen type I expression in human uterine leiomyoma and myometrial cells.

Authors:  Xiaohua Gao; Linda Yu; Lysandra Castro; Alicia B Moore; Tonia Hermon; Carl Bortner; Maria Sifre; Darlene Dixon
Journal:  Toxicol Lett       Date:  2010-03-15       Impact factor: 4.372

4.  1,25-dihydroxyvitamin D3 treatment shrinks uterine leiomyoma tumors in the Eker rat model.

Authors:  Sunil K Halder; Chakradhari Sharan; Ayman Al-Hendy
Journal:  Biol Reprod       Date:  2012-04-19       Impact factor: 4.285

Review 5.  A new hypothesis about the origin of uterine fibroids based on gene expression profiling with microarrays.

Authors:  Phyllis C Leppert; William H Catherino; James H Segars
Journal:  Am J Obstet Gynecol       Date:  2006-04-25       Impact factor: 8.661

6.  Gonadotropin-releasing hormone agonist increases expression of osmotic response genes in leiomyoma cells.

Authors:  Desireé M McCarthy-Keith; Minnie Malik; Joy Britten; James Segars; William H Catherino
Journal:  Fertil Steril       Date:  2011-04-15       Impact factor: 7.329

7.  Surgical and Conservative Management of Symptomatic Leiomyomas during Pregnancy: a Retrospective Pilot Study.

Authors:  R Rothmund; F A Taran; B Boeer; M Wallwiener; H Abele; R Campo; D Wallwiener; S Brucker; K Rall
Journal:  Geburtshilfe Frauenheilkd       Date:  2013-04       Impact factor: 2.915

Review 8.  The expression and potential regulatory function of microRNAs in the pathogenesis of leiomyoma.

Authors:  Xiaoping Luo; Nasser Chegini
Journal:  Semin Reprod Med       Date:  2008-10-24       Impact factor: 1.303

9.  Gene therapy targeting leiomyoma: adenovirus-mediated delivery of dominant-negative estrogen receptor gene shrinks uterine tumors in Eker rat model.

Authors:  Memy H Hassan; Salama A Salama; Dong Zhang; Hossam M M Arafa; Farid M A Hamada; Hala Fouad; Cheryl C Walker; Ayman Al-Hendy
Journal:  Fertil Steril       Date:  2009-01-14       Impact factor: 7.329

10.  Evaluating risk factors for differences in fibroid size and number using a large electronic health record population.

Authors:  Michael J Bray; Eric S Torstenson; Sarah H Jones; Todd L Edwards; Digna R Velez Edwards
Journal:  Maturitas       Date:  2018-05-11       Impact factor: 4.342

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