Literature DB >> 1594612

Cloning of a Rab3 isotype predominantly expressed in adipocytes.

G Baldini1, T Hohl, H Y Lin, H F Lodish.   

Abstract

We have isolated the cDNA for Rab3D, an additional member of the small molecular weight GTP-binding protein family. Rab3D message is abundant in mouse adipocytes. It is increased during differentiation of 3T3-L1 cells into adipocytes, temporally coincident with the appearance of the insulin-sensitive glucose transporter GLUT4. Rab3D is a close homolog of Rab3A, which is found on the cytoplasmic surface of neurosecretory vesicles and which may be involved in their regulated secretion. Since our previous work showed that in permeabilized adipocytes nonhydrolizable GTP analogs mimic insulin in triggering exocytosis of GLUT4-containing vesicles, Rab3D may be involved in the insulin-induced exocytosis of GLUT4-containing vesicles in adipocytes.

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Year:  1992        PMID： 1594612      PMCID： PMC49226          DOI： 10.1073/pnas.89.11.5049

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  29 in total

Review 1.  Making a difference: the role of cell-cell interactions in establishing separate identities for equivalent cells.

Authors:  I Greenwald; G M Rubin
Journal:  Cell       Date:  1992-01-24       Impact factor: 41.582

2.  A glucose transport protein expressed predominately in insulin-responsive tissues.

Authors:  M J Charron; F C Brosius; S L Alper; H F Lodish
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

3.  rab3A attachment to the synaptic vesicle membrane mediated by a conserved polyisoprenylated carboxy-terminal sequence.

Authors:  P A Johnston; B T Archer; K Robinson; G A Mignery; R Jahn; T C Südhof
Journal:  Neuron       Date:  1991-07       Impact factor: 17.173

4.  Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and beta-pancreatic islet cells.

Authors:  B Thorens; H K Sarkar; H R Kaback; H F Lodish
Journal:  Cell       Date:  1988-10-21       Impact factor: 41.582

5.  Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein.

Authors:  M J Birnbaum; H C Haspel; O M Rosen
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

Review 6.  Hormonal regulation of mammalian glucose transport.

Authors:  I A Simpson; S W Cushman
Journal:  Annu Rev Biochem       Date:  1986       Impact factor: 23.643

7.  Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane.

Authors:  S W Cushman; L J Wardzala
Journal:  J Biol Chem       Date:  1980-05-25       Impact factor: 5.157

8.  C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl ester.

Authors:  C C Farnsworth; M Kawata; Y Yoshida; Y Takai; M H Gelb; J A Glomset
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

9.  A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast.

Authors:  B Goud; A Salminen; N C Walworth; P J Novick
Journal:  Cell       Date:  1988-06-03       Impact factor: 41.582

10.  Hypervariable C-terminal domain of rab proteins acts as a targeting signal.

Authors:  P Chavrier; J P Gorvel; E Stelzer; K Simons; J Gruenberg; M Zerial
Journal:  Nature       Date:  1991-10-24       Impact factor: 49.962
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  43 in total

1.  A complete genetic analysis of neuronal Rab3 function.

Authors:  Oliver M Schlüter; Frank Schmitz; Reinhard Jahn; Christian Rosenmund; Thomas C Südhof
Journal:  J Neurosci       Date:  2004-07-21       Impact factor: 6.167

2.  Evidence for protein-mediated fatty acid efflux by adipocytes.

Authors:  A H Henkin; A M Ortegon; S Cho; W-J Shen; A Falcon; F B Kraemer; S-J Lee; A Stahl
Journal:  Acta Physiol (Oxf)       Date:  2011-10-25       Impact factor: 6.311

3.  Rab3D regulates a novel vesicular trafficking pathway that is required for osteoclastic bone resorption.

Authors:  Nathan J Pavlos; Jiake Xu; Dietmar Riedel; Joyce S G Yeoh; Steven L Teitelbaum; John M Papadimitriou; Reinhard Jahn; F Patrick Ross; Ming H Zheng
Journal:  Mol Cell Biol       Date:  2005-06       Impact factor: 4.272

Review 4.  Rabs and their effectors: achieving specificity in membrane traffic.

Authors:  Bianka L Grosshans; Darinel Ortiz; Peter Novick
Journal:  Proc Natl Acad Sci U S A       Date:  2006-08-01       Impact factor: 11.205

5.  Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice.

Authors:  H Ohnishi; L C Samuelson; D I Yule; S A Ernst; J A Williams
Journal:  J Clin Invest       Date:  1997-12-15       Impact factor: 14.808

6.  Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag.

Authors:  Y T Chen; C Holcomb; H P Moore
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-15       Impact factor: 11.205

7.  Insulin-induced translocation of the glucose transporter GLUT4 in cardiac muscle: studies on the role of small-molecular-mass GTP-binding proteins.

Authors:  I Uphues; T Kolter; B Goud; J Eckel
Journal:  Biochem J       Date:  1994-07-01       Impact factor: 3.857

8.  Identification of a nonneuronal isoform of synaptotagmin.

Authors:  A W Hudson; M J Birnbaum
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-20       Impact factor: 11.205

9.  Roles of insulin, guanosine 5'-[gamma-thio]triphosphate and phorbol 12-myristate 13-acetate in signalling pathways of GLUT4 translocation.

Authors:  M Todaka; H Hayashi; T Imanaka; Y Mitani; S Kamohara; K Kishi; K Tamaoka; F Kanai; M Shichiri; N Morii; S Narumiya; Y Ebina
Journal:  Biochem J       Date:  1996-05-01       Impact factor: 3.857

10.  Structure of the murine rab3A gene: correlation of genomic organization with antibody epitopes.

Authors:  M Baumert; G Fischer von Mollard; R Jahn; T C Südhof
Journal:  Biochem J       Date:  1993-07-01       Impact factor: 3.857
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