Literature DB >> 15944357

A 1927 study supports a current genetic model for inheritance of human scalp hair-whorl orientation and hand-use preference traits.

Amar J S Klar1.   

Abstract

The basis of right- vs. left-hand-use preference in humans has been debated for a long time. Culturally learned, birth stress, and biologically specified causes are the prominent etiologies under consideration. A 2003 (Klar 2003) study reported a correlation between a person's preferred hand and the scalp hair-whorl orientation developed on the head. By reinterpreting results of a 1927 (Schwarzburg 1927) study on the genetics of the hair-whorl trait, support for a recent single gene, two-allele "random-recessive model" for both hair-whorl orientation and handedness trait inheritance is demonstrated.

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Year:  2005        PMID: 15944357      PMCID: PMC1449791          DOI: 10.1534/genetics.104.039990

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  8 in total

1.  The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders.

Authors:  Amar J S Klar
Journal:  Genetics       Date:  2002-04       Impact factor: 4.562

2.  Commentary on Klar.

Authors:  Lee Ehrman; Ira B Perelle
Journal:  Genetics       Date:  2004-08       Impact factor: 4.562

Review 3.  An epigenetic hypothesis for human brain laterality, handedness, and psychosis development.

Authors:  A J S Klar
Journal:  Cold Spring Harb Symp Quant Biol       Date:  2004

4.  Handedness, with Special Reference to Twins.

Authors:  D C Rife
Journal:  Genetics       Date:  1940-03       Impact factor: 4.562

Review 5.  A single locus, RGHT, specifies preference for hand utilization in humans.

Authors:  A J Klar
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1996

6.  Excess of counterclockwise scalp hair-whorl rotation in homosexual men.

Authors:  Amar J S Klar
Journal:  J Genet       Date:  2004-12       Impact factor: 1.166

7.  Human handedness and scalp hair-whorl direction develop from a common genetic mechanism.

Authors:  Amar J S Klar
Journal:  Genetics       Date:  2003-09       Impact factor: 4.562

8.  A genetic mechanism implicates chromosome 11 in schizophrenia and bipolar diseases.

Authors:  Amar J S Klar
Journal:  Genetics       Date:  2004-08       Impact factor: 4.562

  8 in total
  5 in total

1.  A proposal for re-defining the way the aetiology of schizophrenia and bipolar human psychiatric diseases is investigated.

Authors:  Amar J S Klar
Journal:  J Biosci       Date:  2010-03       Impact factor: 1.826

Review 2.  From cytoskeletal dynamics to organ asymmetry: a nonlinear, regulative pathway underlies left-right patterning.

Authors:  Gary McDowell; Suvithan Rajadurai; Michael Levin
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2016-12-19       Impact factor: 6.237

3.  Handedness and time to pregnancy.

Authors:  Jin Liang Zhu; Carsten Obel; Olga Basso; Bodil Hammer Bech; Tine Brink Henriksen; Jørn Olsen
Journal:  Epidemiology       Date:  2009-01       Impact factor: 4.822

Review 4.  Scalp hair-whorl orientation of Japanese individuals is random; hence, the trait's distribution is not genetically determined.

Authors:  Amar J S Klar
Journal:  Semin Cell Dev Biol       Date:  2008-11-13       Impact factor: 7.727

5.  Predicting the Permanent Safe Donor Area for Hair Transplantation in Koreans with Male Pattern Baldness according to the Position of the Parietal Whorl.

Authors:  Jae Hyun Park; Young Cheon Na; Jae Seong Moh; Seung Yong Lee; Seung Hyun You
Journal:  Arch Plast Surg       Date:  2014-05-12
  5 in total

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