Literature DB >> 15943970

Dosage compensation in flies: mechanism, models, mystery.

Tobias Straub1, Ina K Dahlsveen, Peter B Becker.   

Abstract

Dosage compensation involves fine-tuning of gene expression at the level of entire chromosomes. The principles that assure selective targeting of the male X chromosome in Drosophila and the mechanism by which transcription levels are adjusted in a twofold range are still mysterious. We discuss the prevalent models in the context of recent experimental observations.

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Year:  2005        PMID: 15943970     DOI: 10.1016/j.febslet.2005.03.050

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  16 in total

1.  Drosophila melanogaster male somatic cells feminized solely by TraF can collaborate with female germ cells to make functional eggs.

Authors:  Daniel S Evans; Thomas W Cline
Journal:  Genetics       Date:  2006-11-16       Impact factor: 4.562

2.  The Drosophila MSL complex activates the transcription of target genes.

Authors:  Tobias Straub; Gregor D Gilfillan; Verena K Maier; Peter B Becker
Journal:  Genes Dev       Date:  2005-10-01       Impact factor: 11.361

3.  roX RNAs are required for increased expression of X-linked genes in Drosophila melanogaster males.

Authors:  Xinxian Deng; Victoria H Meller
Journal:  Genetics       Date:  2006-10-08       Impact factor: 4.562

4.  Stable chromosomal association of MSL2 defines a dosage-compensated nuclear compartment.

Authors:  Tobias Straub; Martin F Neumann; Matthias Prestel; Elisabeth Kremmer; Christoph Kaether; Christian Haass; Peter B Becker
Journal:  Chromosoma       Date:  2005-11-12       Impact factor: 4.316

Review 5.  ATP-dependent chromatin remodeling complexes in Drosophila.

Authors:  Karim Bouazoune; Alexander Brehm
Journal:  Chromosome Res       Date:  2006       Impact factor: 5.239

6.  Cold-induced alteration in the global structure of the male sex chromosome of In1BM2(reinverted) of Drosophila melanogaster is associated with increased acetylation of histone 4 at lysine 16.

Authors:  S Kulkarni-Shukla; A P Barge; R S Vartak; Anita Kar
Journal:  J Genet       Date:  2008-12       Impact factor: 1.166

7.  The DNA binding CXC domain of MSL2 is required for faithful targeting the Dosage Compensation Complex to the X chromosome.

Authors:  Torsten Fauth; Felix Müller-Planitz; Cornelia König; Tobias Straub; Peter B Becker
Journal:  Nucleic Acids Res       Date:  2010-02-05       Impact factor: 16.971

8.  Chromosome-wide gene-specific targeting of the Drosophila dosage compensation complex.

Authors:  Gregor D Gilfillan; Tobias Straub; Elzo de Wit; Frauke Greil; Rosemarie Lamm; Bas van Steensel; Peter B Becker
Journal:  Genes Dev       Date:  2006-03-17       Impact factor: 11.361

9.  X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila.

Authors:  Gaëlle Legube; Shannon K McWeeney; Martin J Lercher; Asifa Akhtar
Journal:  Genes Dev       Date:  2006-03-17       Impact factor: 11.361

10.  Targeting determinants of dosage compensation in Drosophila.

Authors:  Ina K Dahlsveen; Gregor D Gilfillan; Vladimir I Shelest; Rosemarie Lamm; Peter B Becker
Journal:  PLoS Genet       Date:  2006-02-03       Impact factor: 5.917

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