BACKGROUND: We have reported the advantageous clinical outcome of adding cognitive therapy to medication in the prevention of relapse of bipolar disorder. AIMS: This 30-month study compares the cost-effectiveness of cognitive therapy with standard care. METHOD: We randomly allocated 103 individuals with bipolar 1 disorder tostandard treatment and cognitive therapy plus standard treatment. Service use and costs were measured at 3-month intervals and cost-effectiveness was assessed using the net-benefit approach. RESULTS: The group receiving cognitive therapy had significantly better clinical outcomes. The extra costs were offset by reduced service use elsewhere. The probability of cognitive therapy being cost-effective was high and robust to different therapy prices. CONCLUSIONS: Combination of cognitive therapy and mood stabilizers was superior to mood stabilizers alone in terms of clinical outcome and cost-effectiveness for those with frequent relapses of bipolar disorder.
RCT Entities:
BACKGROUND: We have reported the advantageous clinical outcome of adding cognitive therapy to medication in the prevention of relapse of bipolar disorder. AIMS: This 30-month study compares the cost-effectiveness of cognitive therapy with standard care. METHOD: We randomly allocated 103 individuals with bipolar 1 disorder to standard treatment and cognitive therapy plus standard treatment. Service use and costs were measured at 3-month intervals and cost-effectiveness was assessed using the net-benefit approach. RESULTS: The group receiving cognitive therapy had significantly better clinical outcomes. The extra costs were offset by reduced service use elsewhere. The probability of cognitive therapy being cost-effective was high and robust to different therapy prices. CONCLUSIONS: Combination of cognitive therapy and mood stabilizers was superior to mood stabilizers alone in terms of clinical outcome and cost-effectiveness for those with frequent relapses of bipolar disorder.
Authors: Gemma Elizabeth Shields; Deborah Buck; Jamie Elvidge; Karen Petra Hayhurst; Linda Mary Davies Journal: Int J Technol Assess Health Care Date: 2019-07-22 Impact factor: 2.188
Authors: Anastacia Y Kudinova; Heather A MacPherson; Katharine Musella; Elana Schettini; Anna C Gilbert; Gracie A Jenkins; Lee Anna Clark; Daniel P Dickstein Journal: Suicide Life Threat Behav Date: 2020-08-31