| Literature DB >> 15927263 |
Zahra Afrasiabi1, Ekk Sinn, Weisheng Lin, Yinfa Ma, Charles Campana, Subhash Padhye.
Abstract
Ni(II) complexes of ortho-naphthaquinone thiosemicarbazone and semicarbazone were synthesized and spectroscopically characterized. The X-ray crystal structure of both the complexes describe a distorted octahedral coordination with two tridentate mono-deprotonated ligands. In vitro anticancer studies on MCF-7 human breast cancer cells reveal that the semicarbazone derivative along with its nickel complex is more active in the inhibition of cell proliferation than the thiosemicarbazone analogue.Entities:
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Year: 2005 PMID： 15927263 DOI： 10.1016/j.jinorgbio.2005.04.012
Source DB: PubMed Journal: J Inorg Biochem ISSN： 0162-0134 Impact factor: 4.155