Literature DB >> 15922310

Mu opioid receptor-containing neurons mediate electroacupuncture-produced anti-hyperalgesia in rats with hind paw inflammation.

Rui-Xin Zhang1, Linbo Wang, Bing Liu, Jian-Tian Qiao, Ke Ren, Brian M Berman, Lixing Lao.   

Abstract

Previous studies showed that electroacupuncture (EA) significantly attenuates inflammatory hyperalgesia in a complete Freund's adjuvant (CFA)-induced inflammatory pain rat model. The present study demonstrates that pretreatment with Derm-sap, a selective toxin for neurons that contain mu opioid receptor (MOR), specifically decreases MOR and blocks EA anti-hyperalgesia. These data suggest that spinal MOR-containing neurons are involved in the processes by which EA produces anti-hyperalgesia.

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Year:  2005        PMID： 15922310     DOI： 10.1016/j.brainres.2005.05.008

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  5 in total

1.  The status and future of acupuncture mechanism research.

Authors:  Vitaly Napadow; Andrew Ahn; John Longhurst; Lixing Lao; Elisabet Stener-Victorin; Richard Harris; Helene M Langevin
Journal:  J Altern Complement Med       Date:  2008-09       Impact factor: 2.579

2.  Effect of electro-acupuncture stimulation of Ximen (PC4) and Neiguan (PC6) on remifentanil-induced breakthrough pain following thoracal esophagectomy.

Authors:  Yan-Hu Xie; Xiao-Qing Chai; Yue-Lan Wang; Yan-Chun Gao; Jun Ma
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2014-08-19

3.  Effect of electroacupuncture on visceral hyperalgesia, serotonin and fos expression in an animal model of irritable bowel syndrome.

Authors:  Justin Cy Wu; Eric Tc Ziea; Lixing Lao; Emma Fc Lam; Catherine Sm Chan; Angela Yq Liang; Sunny Lh Chu; David Tw Yew; Brian M Berman; Joseph Jy Sung
Journal:  J Neurogastroenterol Motil       Date:  2010-07-26       Impact factor: 4.924

4.  Inhibition of the ubiquitin-proteasome activity prevents glutamate transporter degradation and morphine tolerance.

Authors:  Liling Yang; Shuxing Wang; Grewo Lim; Backil Sung; Qing Zeng; Jianren Mao
Journal:  Pain       Date:  2008-11-04       Impact factor: 7.926

5.  CXCL10 controls inflammatory pain via opioid peptide-containing macrophages in electroacupuncture.

Authors:  Ying Wang; Rebekka Gehringer; Shaaban A Mousa; Dagmar Hackel; Alexander Brack; Heike L Rittner
Journal:  PLoS One       Date:  2014-04-14       Impact factor: 3.240
  5 in total

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