Literature DB >> 15921439

Paecilosetin, a new bioactive fungal metabolite from a New Zealand isolate of Paecilomyces farinosus.

Gerhard Lang1, John W Blunt, Nicholas J Cummings, Anthony L J Cole, Murray H G Munro.   

Abstract

A new tetramic acid derivative, paecilosetin (1), along with a recently characterized N-hydroxypyridone, farinosone B (2), was isolated from the fungus Paecilomyces farinosus. Each compound showed activity against the P388 cell line with IC50 values of 3.1 and 1.1 microg/mL, respectively. Paecilosetin was also active against the microorganisms Bacillus subtilis, Trichophyton mentagrophytes, and Cladosporium resinae.

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Year:  2005        PMID： 15921439     DOI： 10.1021/np0500979

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  12 in total

1.  Creation of an HDAC-based yeast screening method for evaluation of marine-derived actinomycetes: discovery of streptosetin A.

Authors:  Taro Amagata; Jing Xiao; Yi-Pei Chen; Nicholas Holsopple; Allen G Oliver; Trevor Gokey; Anton B Guliaev; Katsuhiko Minoura
Journal:  J Nat Prod       Date:  2012-11-20       Impact factor: 4.050

2.  Reduction of matrix metalloproteinase-9 expression by culture filtrate of Paecilomyces farinosus J3.

Authors:  Hyun-Jin Lee; Chul-Hong Park; Hyung-U Son; Jin-Chul Heo; Sung-Hee Nam; Kwang-Gil Lee; Joo-Hong Yeo; Cheol-Sik Yoon; Jong-Myeung Kim; Yong-Kyu Shin; Si-Oh Kim; Sang-Han Lee
Journal:  Exp Ther Med       Date:  2011-01-20       Impact factor: 2.447

3.  Nature-inspired total synthesis of (-)-fusarisetin A.

Authors:  Jing Xu; Eduardo J E Caro-Diaz; Lynnie Trzoss; Emmanuel A Theodorakis
Journal:  J Am Chem Soc       Date:  2012-03-08       Impact factor: 15.419

4.  Analysis of chemical constituents, antimicrobial and anticancer activities of dichloromethane extracts of Sordariomycetes sp. endophytic fungi isolated from Strobilanthes crispus.

Authors:  Elaine Chin Jinfeng; Mohamed Ikhtifar Mohamad Rafi; Khoo Chai Hoon; Ho Kok Lian; Cheah Yoke Kqueen
Journal:  World J Microbiol Biotechnol       Date:  2016-11-14       Impact factor: 3.312

5.  Fusarisetin A: Scalable Total Synthesis and Related Studies.

Authors:  Jing Xu; Eduardo J E Caro-Diaz; Michelle H Lacoske; Chao-I Hung; Colin Jamora; Emmanuel A Theodorakis
Journal:  Chem Sci       Date:  2012-08-23       Impact factor: 9.825

6.  Nematicidal activity of Paecilomyces spp. and isolation of a novel active compound.

Authors:  Ya-Jun Liu; Chong-Yan Zhai; Yi Liu; Ke-Qin Zhang
Journal:  J Microbiol       Date:  2009-06-26       Impact factor: 3.422

7.  A general diastereoselective catalytic vinylogous aldol reaction among tetramic acid-derived pyrroles.

Authors:  Jonathan G David; Wen-Ju Bai; Marisa G Weaver; Thomas R R Pettus
Journal:  Org Lett       Date:  2014-08-13       Impact factor: 6.005

8.  Cytotoxic and antibacterial activities of endophytic fungi isolated from plants at the National Park, Pahang, Malaysia.

Authors:  Nurul A M N Hazalin; Kalavathy Ramasamy; Siong Meng Lim; Ibtisam Abdul Wahab; Anthony L J Cole; Abu Bakar Abdul Majeed
Journal:  BMC Complement Altern Med       Date:  2009-11-21       Impact factor: 3.659

9.  Pre-fractionated microbial samples--the second generation natural products library at Wyeth.

Authors:  Melissa M Wagenaar
Journal:  Molecules       Date:  2008-06-20       Impact factor: 4.411

10.  Culture conditions and nutrition requirements for the mycelial growth of Isaria farinosa (Hypocreales: Cordycipitaceae) and the altitude effect on its growth and metabolome.

Authors:  Fei Liu; Meichun Xiang; Yanlei Guo; Xiaoli Wu; Guangxin Lu; Yong Yang; Xingzhong Liu; Shijiang Chen; Guozhen Zhang; Wangpeng Shi
Journal:  Sci Rep       Date:  2018-10-23       Impact factor: 4.379
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