Literature DB >> 1591946

In vitro susceptibility of yeast isolates from the blood to fluconazole and amphotericin B.

H Dermoumi1.   

Abstract

221 yeast strains including 131 of Candida albicans, 21 of C. tropicals, 23 of C. parapsilosis, 19 of C. glabrata, 7 of C. guilliermondii, 6 of C. krusei and of other species were isolated from the blood. The activity of fluconazole and amphotericin B was investigated by means of a photometer-read broth microdilution method measuring the 30% inhibitory concentrations (IC30). The results of fluconazole showed a higher susceptibility of C. albicans compared to the other species. However, 6 (4.5%) resistant strains of C. albicans were found. Low sensitivity and resistance were evaluated for C. krusei and C. glabrata strains. All isolates showed susceptibility to amphotericin B.

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Year:  1992        PMID： 1591946     DOI： 10.1159/000238950

Source DB:  PubMed          Journal:  Chemotherapy        ISSN： 0009-3157            Impact factor:   2.544


  7 in total

1.  Selection of Candida glabrata strains with reduced susceptibility to azoles in four liver transplant patients with invasive candidiasis.

Authors:  J Fortún; A López-San Román; J J Velasco; A Sánchez-Sousa; E de Vicente; J Nuño; C Quereda; R Bárcena; G Monge; A Candela; A Honrubia; A Guerrero
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1997-04       Impact factor: 3.267

2.  Comparative evaluation of National Committee for Clinical Laboratory Standards broth macrodilution and agar dilution screening methods for testing fluconazole susceptibility of Cryptococcus neoformans.

Authors:  W R Kirkpatrick; R K McAtee; S G Revankar; A W Fothergill; D I McCarthy; M G Rinaldi; T F Patterson
Journal:  J Clin Microbiol       Date:  1998-05       Impact factor: 5.948

Review 3.  Fluconazole. An update of its antimicrobial activity, pharmacokinetic properties, and therapeutic use in vaginal candidiasis.

Authors:  C M Perry; R Whittington; D McTavish
Journal:  Drugs       Date:  1995-06       Impact factor: 9.546

4.  Antifungal susceptibility testing of yeasts: evaluation of technical variables for test automation.

Authors:  F C Odds; L Vranckx; F Woestenborghs
Journal:  Antimicrob Agents Chemother       Date:  1995-09       Impact factor: 5.191

5.  Fluconazole disk diffusion susceptibility testing of Candida species.

Authors:  W R Kirkpatrick; T M Turner; A W Fothergill; D I McCarthy; S W Redding; M G Rinaldi; T F Patterson
Journal:  J Clin Microbiol       Date:  1998-11       Impact factor: 5.948

6.  Frequency, pathogenicity and microbiologic outcome of non-Candida albicans candiduria.

Authors:  D J Occhipinti; P O Gubbins; P Schreckenberger; L H Danziger
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1994-06       Impact factor: 3.267

7.  Mechanism of fluconazole resistance in Candida krusei.

Authors:  A S Orozco; L M Higginbotham; C A Hitchcock; T Parkinson; D Falconer; A S Ibrahim; M A Ghannoum; S G Filler
Journal:  Antimicrob Agents Chemother       Date:  1998-10       Impact factor: 5.191
  7 in total

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