Literature DB >> 15917558

In vitro activity of doripenem (S-4661) against multidrug-resistant gram-negative bacilli isolated from patients with cystic fibrosis.

Yunhua Chen1, Elizabeth Garber, Qiuqu Zhao, Yigong Ge, Matthew A Wikler, Koné Kaniga, Lisa Saiman.   

Abstract

Doripenem 50% inhibitory concentrations (MIC50) and 90% inhibitory concentrations (MIC90) for multidrug-resistant strains of mucoid Pseudomonas aeruginosa (n=200 strains), nonmucoid P. aeruginosa (n=200), and Burkholderia cepacia complex (n=200) isolated from patients with cystic fibrosis were 8 and 32, 8 and 64, and 8 and 32 microg/ml, respectively. Doripenem had somewhat better activity than established antimicrobial agents.

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Year:  2005        PMID: 15917558      PMCID: PMC1140534          DOI: 10.1128/AAC.49.6.2510-2511.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  9 in total

1.  Comparative in vitro activity of S-4661, a new parenteral carbapenem, and other antimicrobial agents against respiratory pathogens.

Authors:  A Watanabe; H Takahashi; T Kikuchi; T Kobayashi; K Gomi; S Fujimura; Y Tokue; T Nukiwa
Journal:  Chemotherapy       Date:  2000 May-Jun       Impact factor: 2.544

2.  In vitro antimicrobial activity of doripenem, a new carbapenem.

Authors:  Yigong Ge; Matthew A Wikler; Daniel F Sahm; Renée S Blosser-Middleton; James A Karlowsky
Journal:  Antimicrob Agents Chemother       Date:  2004-04       Impact factor: 5.191

3.  Antibiotic susceptibility of multiply resistant Pseudomonas aeruginosa isolated from patients with cystic fibrosis, including candidates for transplantation.

Authors:  L Saiman; F Mehar; W W Niu; H C Neu; K J Shaw; G Miller; A Prince
Journal:  Clin Infect Dis       Date:  1996-09       Impact factor: 9.079

Review 4.  Burkholderia cepacia epidemiology and pathogenesis: implications for infection control.

Authors:  J J LiPuma
Journal:  Curr Opin Pulm Med       Date:  1998-11       Impact factor: 3.155

5.  In vitro and in vivo antibacterial activities of S-4661, a new carbapenem.

Authors:  M Tsuji; Y Ishii; A Ohno; S Miyazaki; K Yamaguchi
Journal:  Antimicrob Agents Chemother       Date:  1998-01       Impact factor: 5.191

6.  The efficacy and safety of meropenem and tobramycin vs ceftazidime and tobramycin in the treatment of acute pulmonary exacerbations in patients with cystic fibrosis.

Authors:  Jeffrey L Blumer; Lisa Saiman; Michael W Konstan; David Melnick
Journal:  Chest       Date:  2005-10       Impact factor: 9.410

Review 7.  Microbiology of airway disease in patients with cystic fibrosis.

Authors:  P H Gilligan
Journal:  Clin Microbiol Rev       Date:  1991-01       Impact factor: 26.132

Review 8.  Infection control recommendations for patients with cystic fibrosis: Microbiology, important pathogens, and infection control practices to prevent patient-to-patient transmission.

Authors:  Lisa Saiman; Jane Siegel
Journal:  Am J Infect Control       Date:  2003-05       Impact factor: 2.918

9.  Comparative activities of doripenem versus isolates, mutants, and transconjugants of Enterobacteriaceae and Acinetobacter spp. with characterized beta-lactamases.

Authors:  Shazad Mushtaq; Yigong Ge; David M Livermore
Journal:  Antimicrob Agents Chemother       Date:  2004-04       Impact factor: 5.191

  9 in total
  8 in total

1.  Spontaneous Bacterial Peritonitis by Burkholderia cepacia Complex: A Rare, Difficult to Treat Infection in Decompensated Cirrhotic Patients.

Authors:  Sunil Taneja; Pramod Kumar; Vikas Gautam; Ajay Duseja; Virendra Singh; Radha K Dhiman; Yogesh Chawla
Journal:  J Clin Exp Hepatol       Date:  2016-08-28

2.  In vivo pharmacodynamic profiling of doripenem against Pseudomonas aeruginosa by simulating human exposures.

Authors:  Aryun Kim; Mary Anne Banevicius; David P Nicolau
Journal:  Antimicrob Agents Chemother       Date:  2008-05-05       Impact factor: 5.191

Review 3.  Cefepime: a reappraisal in an era of increasing antimicrobial resistance.

Authors:  Andrea Endimiani; Federico Perez; Robert A Bonomo
Journal:  Expert Rev Anti Infect Ther       Date:  2008-12       Impact factor: 5.091

4.  MIC score, a new tool to compare bacterial susceptibility to antibiotics application to the comparison of susceptibility to different penems of clinical strains of Pseudomonas aeruginosa.

Authors:  Cédric Bretonnière; Adeline Maitte; Jocelyne Caillon; Gilles Potel; David Boutoille; Cédric Jacqueline; Christophe Guitton
Journal:  J Antibiot (Tokyo)       Date:  2016-03-30       Impact factor: 2.649

Review 5.  New antimicrobial strategies in cystic fibrosis.

Authors:  Mireille van Westreenen; Harm A W M Tiddens
Journal:  Paediatr Drugs       Date:  2010-12-01       Impact factor: 3.022

Review 6.  Doripenem: a review of its use in the treatment of bacterial infections.

Authors:  Susan J Keam
Journal:  Drugs       Date:  2008       Impact factor: 9.546

7.  Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis.

Authors:  Kim L Credito; Lois M Ednie; Peter C Appelbaum
Journal:  Antimicrob Agents Chemother       Date:  2007-10-15       Impact factor: 5.191

8.  Characteristics of doripenem: a new broad-spectrum antibiotic.

Authors:  Francisco Alvarez-Lerma; Santiago Grau; Olivia Ferrández
Journal:  Drug Des Devel Ther       Date:  2009-09-21       Impact factor: 4.162

  8 in total

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