| Literature DB >> 15916418 |
Xin-Shan Ye1, Fang Sun, Min Liu, Qin Li, Yuhang Wang, Guisheng Zhang, Li-He Zhang, Xiao-Lian Zhang.
Abstract
Several iminosugar derivatives were synthesized, and their effects on the secretion of IL-4 and IFN-gamma from the mouse splenocytes were examined. The effects on membrane expression of other T cell-associated molecules (CD3, CD4, CD8) and B cell-associated molecules (CD19) were also investigated. The experimental data demonstrated that synthetic iminosugars hold potential as immunosuppressive agents.Entities:
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Year: 2005 PMID： 15916418 DOI： 10.1021/jm050169t
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446