Literature DB >> 15912555

Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5.

Michael Gartner1, Nils Sunder-Plassmann, Jeanette Seiler, Mathias Utz, Isabelle Vernos, Thomas Surrey, Athanassios Giannis.   

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Year:  2005        PMID： 15912555     DOI： 10.1002/cbic.200500005

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  30 in total

1.  Dimeric Eg5 maintains processivity through alternating-site catalysis with rate-limiting ATP hydrolysis.

Authors:  Troy C Krzysiak; Susan P Gilbert
Journal:  J Biol Chem       Date:  2006-10-23       Impact factor: 5.157

2.  Pathway of ATP hydrolysis by monomeric kinesin Eg5.

Authors:  Jared C Cochran; Troy C Krzysiak; Susan P Gilbert
Journal:  Biochemistry       Date:  2006-10-10       Impact factor: 3.162

3.  Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5.

Authors:  Xiao-dong Sun; Xing-juan Shi; Xiao-ou Sun; You-guang Luo; Xiao-jing Wu; Chang-fu Yao; Hai-yang Yu; Deng-wen Li; Min Liu; Jun Zhou
Journal:  Acta Pharmacol Sin       Date:  2011-10-10       Impact factor: 6.150

4.  3D-QSAR studies of dihydropyrazole and dihydropyrrole derivatives as inhibitors of human mitotic kinesin Eg5 based on molecular docking.

Authors:  Xingyan Luo; Mao Shu; Yuanqiang Wang; Jin Liu; Wenjuan Yang; Zhihua Lin
Journal:  Molecules       Date:  2012-02-17       Impact factor: 4.411

Review 5.  Kinesins and cancer.

Authors:  Oliver Rath; Frank Kozielski
Journal:  Nat Rev Cancer       Date:  2012-07-24       Impact factor: 60.716

6.  Modulating motility of intracellular vesicles in cortical neurons with nanomagnetic forces on-chip.

Authors:  Anja Kunze; Coleman Tylor Murray; Chanya Godzich; Jonathan Lin; Keegan Owsley; Andy Tay; Dino Di Carlo
Journal:  Lab Chip       Date:  2017-02-28       Impact factor: 6.799

7.  Synthesis of novel perillyl-dihydropyrimidinone hybrids designed for antiproliferative activity.

Authors:  Vinicius Vendrusculo; Vanessa P de Souza; Luiz Antônio M Fontoura; Marcelo G M D'Oca; Thais P Banzato; Paula A Monteiro; Ronaldo A Pilli; João Ernesto de Carvalho; Dennis Russowsky
Journal:  Medchemcomm       Date:  2018-07-31       Impact factor: 3.597

8.  Computational analysis of image-based drug profiling predicts synergistic drug combinations: applications in triple-negative breast cancer.

Authors:  Miriam B Brandl; Eddy Pasquier; Fuhai Li; Dominik Beck; Sufang Zhang; Hong Zhao; Maria Kavallaris; Stephen T C Wong
Journal:  Mol Oncol       Date:  2014-06-19       Impact factor: 6.603

9.  Small molecule screen for candidate antimalarials targeting Plasmodium Kinesin-5.

Authors:  Liqiong Liu; Jessica Richard; Sunyoung Kim; Edward J Wojcik
Journal:  J Biol Chem       Date:  2014-04-15       Impact factor: 5.157

10.  UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit.

Authors:  Mathew J Garnett; Jörg Mansfeld; Colin Godwin; Takahiro Matsusaka; Jiahua Wu; Paul Russell; Jonathon Pines; Ashok R Venkitaraman
Journal:  Nat Cell Biol       Date:  2009-10-11       Impact factor: 28.824
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