| Literature DB >> 15908210 |
Prasad P Dixit1, Prathap S Nair, Vijaykumar J Patil, Sanjay Jain, Sudershan K Arora, Neelima Sinha.
Abstract
A series of novel (un)substituted benzotriazolyl oxazolidinone derivatives has been synthesized and tested for in vitro antibacterial activities by MIC determination against a panel of susceptible and resistant Gram-positive and Gram-negative microorganisms, some of which are resistant to methicillin and vancomycin. Compounds 20, 21, 24, 29 and 30 from this series were found to be equipotent or more potent than linezolid in vitro.Entities:
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Year: 2005 PMID： 15908210 DOI： 10.1016/j.bmcl.2005.04.045
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823