Literature DB >> 15905094

Synthesis and structure-activity relationships of 2-alkylidenethiazolidine-4,5-diones as antibiotic agents.

Uwe Albrecht1, Dirk Gördes, Enrico Schmidt, Kerstin Thurow, Michael Lalk, Peter Langer.   

Abstract

2-Alkylidenethiazolidine-4,5-diones were prepared by novel one-pot cyclizations of arylacetonitriles with isothiocyanates and ethyl 2-chloro-2-oxoacetate. The products show antibiotic activity against the Gram-positive bacteria Bacillus subtilis and Staphylococcus aureus.

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Year:  2005        PMID： 15905094     DOI： 10.1016/j.bmc.2005.04.046

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  3 in total

1.  Green Synthesis of Thiazolidine-2,4-dione Derivatives and Their Lipoxygenase Inhibition Activity With QSAR and Molecular Docking Studies.

Authors:  Melita Lončarić; Ivica Strelec; Valentina Pavić; Vesna Rastija; Maja Karnaš; Maja Molnar
Journal:  Front Chem       Date:  2022-07-05       Impact factor: 5.545

2.  {3-[(2-Chloro-1,3-thia-zol-4-yl)meth-yl]-1,3-thia-zolidin-2-yl-idene-amino}-formonitrile.

Authors:  Ying-Qi Li
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-09-11

3.  Diversity-oriented synthesis of spirothiazolidinediones and their biological evaluation.

Authors:  Sambasivarao Kotha; Gaddamedi Sreevani; Lilya U Dzhemileva; Milyausha M Yunusbaeva; Usein M Dzhemilev; Vladimir A D'yakonov
Journal:  Beilstein J Org Chem       Date:  2019-11-18       Impact factor: 2.883
  3 in total

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