| Literature DB >> 15904646 |
Masami Kosuge1, Kazuo Kimura, Toshiyuki Ishikawa, Toshiaki Ebina, Tomoaki Shimizu, Kiyoshi Hibi, Noritaka Toda, Yoshio Tahara, Kengo Tsukahara, Masahiko Kanna, Jyunn Okuda, Naoki Nozawa, Hiroyuki Ozaki, Hideto Yano, Satoshi Umemura.
Abstract
To identify an early, simple, noninvasive predictor of left main (LM) or 3-vessel disease (3-VD), we retrospectively studied clinical variables on admission in 310 patients with acute coronary syndromes with non-ST-segment elevation. Univariate analysis indicated that many factors were related to LM/3-VD. Multivariate analysis showed that ST-segment elevation in lead aVR of >/=0.5 mm was the strongest predictor of LM/3-VD, followed by positive troponin T (odds ratio 19.7, p <0.001, and odds ratio 3.08, p = 0.048, respectively). ST-segment elevation in lead aVR of >/=0.5 mm and positive troponin T identified LM/3-VD with sensitivities of 78% and 62%, specificities of 86% and 59%, positive predictive values of 57% and 26%, and negative predictive values of 95% and 87%, respectively (p <0.05). Our findings suggest that in patients with non-ST-segment elevation acute coronary syndromes, ST-segment elevation in lead aVR of >/=0.5 mm and positive troponin T on admission (especially the former) are useful predictors of LM/3-VD.Entities:
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Year: 2005 PMID： 15904646 DOI： 10.1016/j.amjcard.2005.01.085
Source DB: PubMed Journal: Am J Cardiol ISSN： 0002-9149 Impact factor: 2.778