| Literature DB >> 15896741 |
Stefan Björklund1, Claes M Gustafsson.
Abstract
The Mediator complex acts as a bridge, conveying regulatory information from enhancers and other control elements to the basal RNA polymerase II transcription machinery. Mediator is required for the regulated transcription of nearly all RNA polymerase II-dependent genes in Saccharomyces cerevisiae, and post-translational modifications of specific Mediator subunits can affect global patterns of gene transcription.Entities:
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Year: 2005 PMID： 15896741 DOI： 10.1016/j.tibs.2005.03.008
Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807