PURPOSE: As a result of the putative protective role of lutein and zeaxanthin at the site of the retina (macular pigment [MP]), interest in the noninvasive measurement of these retinal carotenoids is increasing. In principle, any method used to measure MP in vivo should provide spectral absorption curves that match extinction spectra of MP measured ex vivo. METHODS: In this article, we assess published spectral curves with respect to this criterion. RESULTS AND DISCUSSION: Variation in derived MP measures resulting from methodological differences between techniques is noted and discussed.
PURPOSE: As a result of the putative protective role of lutein and zeaxanthin at the site of the retina (macular pigment [MP]), interest in the noninvasive measurement of these retinal carotenoids is increasing. In principle, any method used to measure MP in vivo should provide spectral absorption curves that match extinction spectra of MP measured ex vivo. METHODS: In this article, we assess published spectral curves with respect to this criterion. RESULTS AND DISCUSSION: Variation in derived MP measures resulting from methodological differences between techniques is noted and discussed.
Authors: Tomas S Aleman; Artur V Cideciyan; Elizabeth A M Windsor; Sharon B Schwartz; Malgorzata Swider; John D Chico; Alexander Sumaroka; Alexander Y Pantelyat; Keith G Duncan; Leigh M Gardner; Jessica M Emmons; Janet D Steinberg; Edwin M Stone; Samuel G Jacobson Journal: Invest Ophthalmol Vis Sci Date: 2007-03 Impact factor: 4.799