Literature DB >> 15893017

Synthesis and antifungal activity of 2/3-arylthio- and 2,3-bis(arylthio)-5-hydroxy-/5-methoxy-1,4-naphthoquinones.

Chung-Kyu Ryu1, Ju-Yeon Shim, Mi Jin Chae, Ik Hwa Choi, Ja-Young Han, Ok-Jai Jung, Jung Yoon Lee, Seong Hee Jeong.   

Abstract

2/3-Arylthio- and 2,3-bis(arylthio)-5-hydroxy-/5-methoxy-1,4-naphthoquinones 5-9 were synthesized and tested for in vitro antifungal activity against Candida species and Aspergillus niger. The synthesized compounds 5-9 generally showed good activities against Candida albicans and C. tropicalis. The results suggest that the 1,4-naphthoquinones 5-9 would be potent antifungal agents.

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Year:  2005        PMID: 15893017     DOI: 10.1016/j.ejmech.2004.12.004

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  2 in total

1.  Novel one-pot synthesis of a library of 2-aryloxy-1,4-naphthoquinone derivatives. Determination of antifungal and antibacterial activity.

Authors:  Katherine Chaves-Carballo; Guy V Lamoureux; Alice L Perez; Alexandre Bella Cruz; Valdir Cechinel Filho
Journal:  RSC Adv       Date:  2022-06-23       Impact factor: 4.036

2.  Detoxification Mechanism of 8,8-Dimethyl-3-[(R-phenyl)amino]-1,4,5(8H)-naphthalentrione Derivatives by Botrytis cinerea.

Authors:  Leonora Mendoza; Marcela Vivanco; Ricardo Melo; Paulo Castro; Ramiro Araya-Maturana; Milena Cotoras
Journal:  Molecules       Date:  2019-02-02       Impact factor: 4.411

  2 in total

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